ID A0A1X7IF32_9BACL Unreviewed; 728 AA.
AC A0A1X7IF32;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Penicillin-binding protein 2B {ECO:0000313|EMBL:SMG13318.1};
GN ORFNames=SAMN06295960_0390 {ECO:0000313|EMBL:SMG13318.1};
OS Paenibacillus aquistagni.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1852522 {ECO:0000313|EMBL:SMG13318.1, ECO:0000313|Proteomes:UP000193834};
RN [1] {ECO:0000313|EMBL:SMG13318.1, ECO:0000313|Proteomes:UP000193834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=11 {ECO:0000313|EMBL:SMG13318.1,
RC ECO:0000313|Proteomes:UP000193834};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; FXAZ01000001; SMG13318.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7IF32; -.
DR STRING; 1852522.SAMN06295960_0390; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000193834; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR Gene3D; 3.30.10.20; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193834};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 609..669
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 728 AA; 81376 MW; 7B70FDF979A5EC4E CRC64;
MVKRIKLRTL FIGGLFLLFF IIIISRLFWY QVWNRDFWLD LAQATWSTEQ EIPAKRGTIY
DKNGEVLAMD APAYNVVLNP KVIQTLRTNE KLVEKHIDVE RLIVEKLHEV LGKPESELYE
LARKKRDSGE YHIYREVRKE GWMIEQEPYD ELNAFIQEKE DEWKVNDIGL YLLKDTKRFY
AKNNLAAHVL GYMNKENEPV GGIESQFNSM LQGKPGSIQY DKDRQGTKLP TASEVYTPAE
DGKNLYLTID ATIQQYIQEA ITGVYERYSP YSISVIAADP KTGDVLGMAN LPTYDPNKYW
EAATDLRNFY NPAIMSTYEP GSTFKIVTLA ASVQEGVFDP NETYKSGSIV AGGRPIRDHN
HVGWGTITYL EGLKRSSNVA FVKLGFEKLR EDQFKSYIDN FGFGEKTGIE LPGENAGKIH
FQYAADIAAA TYGHGQLTVT PIQQIMAVSA VANGGKLMVP HIVKKVEDSQ TGEVQERAPE
VVREVLKPEM AKQVSEYLEQ VVADQQIGTG KAAYIEGYRV AGKTGTALKV IDGGYDTTRA
VVSFIGYAPV EDPRIAVLVV VDDPKDYYEG GGFVAPVIFK EIVSKSLRYM GVPTSHQSGD
EADHRDGQAV TLATTPNVQG LKPDAAKQKL AEKGIVFETV GSGNEVKRQY PEPGTKLAVG
QRVYLLTQEP SQLKLPNLTG KSLRDVVELA SLLQWEVKAE GEGYVTEYAI STKNNTKVVY
VKLKPKIP
//
