ID A0A1X7IQB8_9BACT Unreviewed; 211 AA.
AC A0A1X7IQB8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family {ECO:0000313|EMBL:SMG17014.1};
GN ORFNames=SAMN06275492_10431 {ECO:0000313|EMBL:SMG17014.1};
OS Dethiosulfovibrio salsuginis.
OC Bacteria; Synergistota; Synergistia; Synergistales;
OC Dethiosulfovibrionaceae; Dethiosulfovibrio.
OX NCBI_TaxID=561720 {ECO:0000313|EMBL:SMG17014.1, ECO:0000313|Proteomes:UP000193355};
RN [1] {ECO:0000313|EMBL:SMG17014.1, ECO:0000313|Proteomes:UP000193355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USBA 82 {ECO:0000313|EMBL:SMG17014.1,
RC ECO:0000313|Proteomes:UP000193355};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FXBB01000004; SMG17014.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7IQB8; -.
DR STRING; 561720.SAMN06275492_10431; -.
DR OrthoDB; 9794407at2; -.
DR Proteomes; UP000193355; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd03360; LbH_AT_putative; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR020019; AcTrfase_PglD-like.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF00132; Hexapep; 1.
DR Pfam; PF17836; PglD_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:SMG17014.1};
KW Transferase {ECO:0000313|EMBL:SMG17014.1}.
FT DOMAIN 4..79
FT /note="PglD N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17836"
FT ACT_SITE 132
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT BINDING 67
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 141
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 162
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT SITE 133
FT /note="Increases basicity of active site His"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ SEQUENCE 211 AA; 21580 MW; 65BD5B28D4A28FBE CRC64;
MSGIYVLGAG GHGKVVISTI RAMGLEVEAV LDDDRSLWGS YLSGVEVTGP IDSLRGKKNP
KAIIAIGINH IREKIATRLD EVEWISAIHP SAVIDGSVKI GPGTAIFAGA VVQPDSTVGN
HVIINTGATV DHDCVLEDFV HIAPGCHLAG NVSLRRGAFM GIGSCAVPGT TVGPWTTVGA
GGAVIADLPG NAVAVGVPAK EITALPSKRN R
//
