ID   A0A1X7JGD9_9MICO        Unreviewed;       487 AA.
AC   A0A1X7JGD9;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Flotillin {ECO:0000313|EMBL:SMG26762.1};
GN   ORFNames=SAMN06296010_1365 {ECO:0000313|EMBL:SMG26762.1};
OS   Agreia pratensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Agreia.
OX   NCBI_TaxID=150121 {ECO:0000313|EMBL:SMG26762.1, ECO:0000313|Proteomes:UP000193244};
RN   [1] {ECO:0000313|EMBL:SMG26762.1, ECO:0000313|Proteomes:UP000193244}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM Ac-2510 {ECO:0000313|EMBL:SMG26762.1,
RC   ECO:0000313|Proteomes:UP000193244};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. Flotillin subfamily.
CC       {ECO:0000256|ARBA:ARBA00007161}.
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DR   EMBL; FXAY01000002; SMG26762.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X7JGD9; -.
DR   STRING; 150121.SAMN06296010_1365; -.
DR   OrthoDB; 9786220at2; -.
DR   Proteomes; UP000193244; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd03399; SPFH_flotillin; 1.
DR   Gene3D; 3.30.479.30; Band 7 domain; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR031905; Flotillin_C.
DR   InterPro; IPR027705; Flotillin_fam.
DR   PANTHER; PTHR13806:SF31; FLOTILLIN-LIKE PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR13806; FLOTILLIN-RELATED; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   Pfam; PF15975; Flot; 1.
DR   SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          33..219
FT                   /note="Band 7"
FT                   /evidence="ECO:0000259|Pfam:PF01145"
FT   DOMAIN          353..426
FT                   /note="Flotillin C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15975"
FT   REGION          458..487
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..481
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   487 AA;  51308 MW;  F583312C1657C2B9 CRC64;
     MDFISSNTSI VAVVVVIVII VALLGFVASR IRRVPPNQAL IVVGRGAAKD AASGITSPQK
     VIIGGRTFIW PIFQEGFKLS LEQYQTSVDV TAIDSNFIRT SVKATVNFKV TGSEDGVRRA
     AQRYLLQQAK LPEIVQQSLE GSLRGLIGGR AVDELVKSFA QLAQDAVTET KGELAELGLQ
     IETLNIREIE TPGSTYLADR GRAEAAQARQ IAEVREAETV RAAALSRIEN EQLTAERQRE
     LDIRVASIKA DTERANAEAN AAGELARAEQ ATFVAGKERE AVVEQAKVAE QRLNIEVRQP
     AEAAAYAAVQ KAQADRDTEK AAVDVEVYRR QQTAEAARTA AVNEAESITA LGNANAAATR
     AKGEAEAAAV KALAEAQNLL SREALASRAI DAMPEVARRM AEPLSNVDNI SIISTEGASA
     LTKSVAQNMT ELPEVIKQAT GLDLSALLAG IGGGLAAKSA GTGASSAGRP ATATATPPTP
     ETESPVI
//