ID   A0A1X7ND74_9LACT        Unreviewed;       389 AA.
AC   A0A1X7ND74;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Galactosamine 6-phosphate isomerase AgaS {ECO:0000313|EMBL:SMH34866.1};
GN   ORFNames=SAMN04488700_1728 {ECO:0000313|EMBL:SMH34866.1};
OS   Carnobacterium iners.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC   Carnobacterium.
OX   NCBI_TaxID=1073423 {ECO:0000313|EMBL:SMH34866.1, ECO:0000313|Proteomes:UP000193435};
RN   [1] {ECO:0000313|EMBL:SMH34866.1, ECO:0000313|Proteomes:UP000193435}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG26642 {ECO:0000313|EMBL:SMH34866.1,
RC   ECO:0000313|Proteomes:UP000193435};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-galactosamine 6-phosphate + H2O = D-tagatopyranose 1-
CC         phosphate + NH4(+); Xref=Rhea:RHEA:47680, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:28938, ChEBI:CHEBI:71674, ChEBI:CHEBI:138150;
CC         Evidence={ECO:0000256|ARBA:ARBA00029292};
CC   -!- SIMILARITY: Belongs to the SIS family. AgaS subfamily.
CC       {ECO:0000256|ARBA:ARBA00007748}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FXBJ01000002; SMH34866.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X7ND74; -.
DR   STRING; 1073423.SAMN04488700_1728; -.
DR   OrthoDB; 9779207at2; -.
DR   Proteomes; UP000193435; Unassembled WGS sequence.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05010; SIS_AgaS_like; 1.
DR   CDD; cd05008; SIS_GlmS_GlmD_1; 1.
DR   InterPro; IPR035466; GlmS/AgaS_SIS.
DR   InterPro; IPR035464; SIS_AgaS.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   PANTHER; PTHR32502:SF3; D-GALACTOSAMINE-6-PHOSPHATE DEAMINASE AGAS-RELATED; 1.
DR   PANTHER; PTHR32502; N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED; 1.
DR   SUPFAM; SSF53697; SIS domain; 1.
DR   PROSITE; PS51464; SIS; 2.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Isomerase {ECO:0000313|EMBL:SMH34866.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193435};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          45..202
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
FT   DOMAIN          221..369
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
SQ   SEQUENCE   389 AA;  42913 MW;  8EC898EDD7687835 CRC64;
     MFTLNEEELE NLGATITTRE IAQQPDLWEE AYTTYTERKK DIEEFFEKLT TKNDNMRVIF
     TGAGTSAYVG ETIIPYLKGK VDGKQWDLAA VPTTTLVSNP YQFLKSDIPT LLVSFARSGN
     SPESVASVEL GEQIVKDFYQ LTITCAKEGE LAKRAKGDKN NLLLLMPERS NDQGFAMTGS
     FSCMTLTALL VFDTAKEDEK AAYVKTIRQM GSSVVERVSE IQEVIDGDFD RIIYLGSGSL
     EGLTREAQLK VLELTAGKVV TAFDSSLGFR HGPKSFVNEK ALVFVFVSNQ AYTRKYDLDI
     LKELKLDGIA QSVIAIETTG EQNFDGAAFS FGKEGKDVPD AYLALPYVIY GQTVSLLSSI
     KVGNKPDIPS PTGTVNRIVK GVTIYDYSE
//