ID A0A1X7R045_9SACH Unreviewed; 794 AA.
AC A0A1X7R045;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Similar to Saccharomyces cerevisiae YGL073W HSF1 Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia {ECO:0000313|EMBL:SMN19005.1};
GN ORFNames=KASA_0P01375G {ECO:0000313|EMBL:SMN19005.1};
OS Kazachstania saulgeensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1789683 {ECO:0000313|EMBL:SMN19005.1, ECO:0000313|Proteomes:UP000196158};
RN [1] {ECO:0000313|EMBL:SMN19005.1, ECO:0000313|Proteomes:UP000196158}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|RuleBase:RU004020}.
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DR EMBL; FXLY01000003; SMN19005.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7R045; -.
DR STRING; 1789683.A0A1X7R045; -.
DR OrthoDB; 1117127at2759; -.
DR Proteomes; UP000196158; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015:SF206; HEAT SHOCK FACTOR PROTEIN; 1.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000196158};
KW Stress response {ECO:0000313|EMBL:SMN19005.1}.
FT DOMAIN 224..248
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 490..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 794 AA; 90926 MW; E48C1DA93AD22F6E CRC64;
MKETIKENRP DDSHGQTTDM PMLNDEEIEK ILQPTELFPD EIITPSNNDS NTPSNIETID
GTINNNNNTI ENESLYNKSI ALRNEPTTDI VRSNNRILGM YNQQQSDSQS LPPRQELHSM
NIINSGSSND FQQPTTAANH SRMEQAIHQA TRMPSMTETI YGGISNQQRL TKQSQSQPHK
TRPAFVNKLW SMLNDETNEH LIQWSYDGQS FIVTRREQFV HEVLPRYFKH SNFASFVRQL
NMYGWHKVQD VKAGSIQNSS DDRWQFENPN FIRGREDLLI NIVRQKGNNT STNQHHNNNN
LHNENEFNGL MAGIDNKPML HLMNEPSTYS GMDVRKDVST VLNELETIKY NQIAISKDLL
RINKDNELLW KENMVARERH RTQQQTLEKI FRFLTSMVPH MDQKMLMDGI MNFTDNSNNG
NNGNNNNNNN NNNNNNTNNN GNNGNPIDKN STFDNNSNNN FSNDHKDFND GNSRFHEDVF
DEVIDNTRKN NVKDGNTNNN SNNNNSGINT NSSTNHNNNI NMNDHNGYYV GNSNIRTSTF
DSPSTQFYNE FNNNDGVQDN SHPNIQSYNS YNPYDYMPRH PTQKTRLLLK NRSNSSSSSN
IPTISPNSLN KDSKILELPL DDEELETNPP TVNSTTSKKD DERNDPNIVS SKFLGNIQSN
IDEQDLRIQH LEDMVKGLSP MKDKNDSHNG NAFSLQDYFT SDVLPDTQNN SNSTTSNPQT
QTQTQTQQEH GEGLTPLFYD DNTLLHVTDP PLQTATDNFR SNNHKRKSID NNKSNDVKIE
ELSPEPDLKR PKFT
//
