ID A0A1X7R0T4_9SACH Unreviewed; 709 AA.
AC A0A1X7R0T4;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Similar to Saccharomyces cerevisiae YBR260C RGD1 GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization {ECO:0000313|EMBL:SMN19255.1};
GN ORFNames=KASA_0P04389G {ECO:0000313|EMBL:SMN19255.1};
OS Kazachstania saulgeensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1789683 {ECO:0000313|EMBL:SMN19255.1, ECO:0000313|Proteomes:UP000196158};
RN [1] {ECO:0000313|EMBL:SMN19255.1, ECO:0000313|Proteomes:UP000196158}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FXLY01000003; SMN19255.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7R0T4; -.
DR STRING; 1789683.A0A1X7R0T4; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000196158; Unassembled WGS sequence.
DR GO; GO:0005933; C:cellular bud; IEA:UniProt.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF136; RHO GTPASE-ACTIVATING PROTEIN RGD1; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000196158}.
FT DOMAIN 53..315
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 515..706
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 709 AA; 80030 MW; EEE30C4CD9934D45 CRC64;
MSADSLSASL GDISLSGDEE TSSFQPIKDD QSNKTFNNNN INNDTQNTLL DSPEIQNVMN
SDIAINALLT RLKTSLLTCE EFTKFLRKKY LFEEEHTEEL SKQYKHFFTT TNGVSSLRKM
IHDVLEFDGK LAKVKQSYLT ALQKMYDEIS ALLLTITKMR KSVKENSRRL EKDVVDAIHA
AEKAQSRYIS LCQDYEKVRM ADPSKTKLTL RGSRTTKEQE EDLLRKIDSA DLEYKQRVDH
SDSLRHNFLT RERPRIVQEL KDLILELDTA MAIQLQKYTI WTENLILNSG VTVSPFDKPQ
NSMKGIANSV KNEQDLYNFL NKYNASSKSG LLLNKNLIPV EYKKHPSMAK RRNSVNKAPP
KYAVDPARNS IPKRILSTHN ESPFHPSSST NFGTPIIASN SSSKYASSTP MGTSQLSSTT
SRSFVPLNQP SKPRKSIDTF NGNEKQATVS NNNPNSRNGG NFHSLDPGKG DARMPSISNT
LVSTDTTDSD RPVSYLQTDV RMPAGVQNNF KTFGVPLENL IEYEQDMVPA IVRQCIFVID
KYGLQLEGIY RKSANVLDVS KLKEEIDKDP SNISMILPGN NHSDSDIYLV GSLLKSFFSL
LPDPLVPGII GPELKTCISI EDPKTRKNYM HNLLYKLPDA QYWTLRSLLF HLKRIIANEE
SNRMNQKAVC IIWGPTIVPI NEEDPNDVNY QIASMEVLLD VADQAFEPE
//
