ID   A0A1X7R2S8_9SACH        Unreviewed;       548 AA.
AC   A0A1X7R2S8;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Similar to Saccharomyces cerevisiae YER056C FCY2 Purine-cytosine permease, mediates purine (Adenine, guanine, and hypoxanthine) and cytosine accumulation {ECO:0000313|EMBL:SMN19945.1};
GN   ORFNames=KASA_0O05665G {ECO:0000313|EMBL:SMN19945.1};
OS   Kazachstania saulgeensis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX   NCBI_TaxID=1789683 {ECO:0000313|EMBL:SMN19945.1, ECO:0000313|Proteomes:UP000196158};
RN   [1] {ECO:0000313|EMBL:SMN19945.1, ECO:0000313|Proteomes:UP000196158}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
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DR   EMBL; FXLY01000004; SMN19945.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X7R2S8; -.
DR   OrthoDB; 65220at2759; -.
DR   Proteomes; UP000196158; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd11484; SLC-NCS1sbd_CobB-like; 1.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR012681; NCS1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR   NCBIfam; TIGR00800; ncs1; 1.
DR   PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR   PANTHER; PTHR31806:SF1; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
DR   PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196158};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002744}.
FT   TRANSMEM        105..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        281..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        316..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        359..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        444..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        483..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        522..538
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   548 AA;  60408 MW;  A4AEE4EB591E3AC3 CRC64;
     MGFSIKKLVK HQSEENGSTD ISSDIEQQNY PIVTDEKNTG NEKHAIYESI SNDDDTNDLY
     AIESAIETKL SWFNRLAIYL NAETKGIEPV GEEERNPDES VVNAASMWFS ANMVIAAYAL
     GGLGPMIYQL NFGTSVLVII FFNILGLLPV AYFSLFGCEL GLRQMVLSRF LLGNLTARIF
     ALINVVACVG WGIVNTVVSA QLLNMVNHAS GHECPLWAGC IIIVGCTVAV TFFGYRVIHA
     YEKWSWVPNF AVFLVIIARL AKSHNFSNGE WTSGPTTAGN VLSFGCTVYG FATGWTTYAS
     DYTVYMPKNT NKYKVFFSLV AGLSFPLFFC MILGAASAMG AVNDPTWNQY YQTNSMGGLT
     YAILVPNSLH GFGQFCCVLL AMSTVANNVP NMYTIALSAQ AMWEPFAKVP RVLWTLAGNA
     ATVGIAIPAC YYFEGFMQNF MDSIGYYLAI YTAIALSEHF IYRKNSFRNY NIEDWNDSSK
     LPIGIAGTAA LIVAAFGVAL GMCQTYWVGE ISRLIGDYGG DIGFELGASW AFITYNIIRP
     FEIKYFGR
//