ID A0A1X7R7B8_9SACH Unreviewed; 835 AA.
AC A0A1X7R7B8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 13-SEP-2023, entry version 21.
DE SubName: Full=Similar to Saccharomyces cerevisiae YAL041W CDC24 Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p {ECO:0000313|EMBL:SMN21504.1};
GN ORFNames=KASA_0K01672G {ECO:0000313|EMBL:SMN21504.1};
OS Kazachstania saulgeensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1789683 {ECO:0000313|EMBL:SMN21504.1, ECO:0000313|Proteomes:UP000196158};
RN [1] {ECO:0000313|EMBL:SMN21504.1, ECO:0000313|Proteomes:UP000196158}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FXLY01000008; SMN21504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7R7B8; -.
DR STRING; 1789683.A0A1X7R7B8; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000196158; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:UniProt.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000196158}.
FT DOMAIN 171..282
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 315..495
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 519..680
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 756..835
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 82..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..721
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 835 AA; 94710 MW; 320F775F4BDC16AD CRC64;
MVVVQANKRP SLSLVESGKS GINIVANNVM NTAVTESDSL YYVCLNIKKR LEVLPQIQPY
LNLAYTSSEL LSERQSLLLS QKQQQQLLEQ QQSSSSQSGN TSSNISNGPN KNSSHRSVSS
NYSNDGFGVL GSTGNSTPTT MRSSSISNIS FKDEFTLDGI TYNSSNGHNS VSMDDTQLTY
SMGILPISMD CDPVTQLAQL FQQGSPLCIL FNTVRPQYKL PVVSSDDLKI CKKSIYDFIL
GCKKHFAFND EELFTISDVF ANSTNQLVKV LEVVTTLMNA APEVFLSTSK VQQMIDAEIE
QNHKSRAQKS KAHEEYDKVI KEFIATERKY VHDLETLDTY KQQLLDNNLI TSEELYMLFP
NLTEVIDFQR RFLISLEINA LVDPQKQRIG ALFMHSKFFF KLYEPWSIGQ NAAIDFLANT
LDKIQDSDLV IKNKLELQSF LYKPVQRLCR YPLLLKELIS CNSHDEKSSG SDNISKELEI
ALDISKRIAM SINENQRRTE NHEVVKKLYG RVSNWKGYRI AKFGELLYYD KVFISTNNSS
EPEREFEVYL FEKIIILFSE IQPKKSSLIL KKKPTSSGSS LTLNLTSSNH HNSFTNISSG
NNSSNSSSIF GSNSNTGNAE PKLDLRGRIM IMNLDQVTPL NSRSLNITWE SIKEQGNFLL
KFKNEETRDN WCACLQSLVR SVKSESYKSN HSENSFVSTT STNTPSDRSH SDKRKDSRAS
NSSLSFKRMS DTLPKQRRRV SNFDMEQKNN NIPENLLVLK ITFDNESFNV SINIDTKFVN
VLDTIQKKVN HDVSKVKYQD EDGDYIVLAS DDDWIVAKDM LKENGEYSLN IWAYS
//
