ID A0A1X7RNK2_ZYMTR Unreviewed; 628 AA.
AC A0A1X7RNK2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=ZT3D7_G3727 {ECO:0000313|EMBL:SMQ48577.1};
OS Zymoseptoria tritici ST99CH_3D7.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=1276538 {ECO:0000313|EMBL:SMQ48577.1, ECO:0000313|Proteomes:UP000215127};
RN [1] {ECO:0000313|EMBL:SMQ48577.1, ECO:0000313|Proteomes:UP000215127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; LT853694; SMQ48577.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7RNK2; -.
DR STRING; 1276538.A0A1X7RNK2; -.
DR Proteomes; UP000215127; Chromosome 3.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000215127}.
FT DOMAIN 90..207
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 70180 MW; F7AB39018AD24985 CRC64;
MWDDEDNNPY GSFHRRNSET SDIVSPTERF NRPSTPPSGN SSPDQQPHFI SRPSDLSDEE
LDDERGRDIK PQPKAGGYDS RIEQILYEHP DLEIQIVYAG KNTEGGGGYI MYTIRTGEIE
VRRRYSEFAS LRQTLVNLHP TLIVPPIPEK HSIADYAAKP TKAKEDLGII ELRQRMLATF
LNRCRRMKEI REDGVWWRFL DPNVSWSEVL HSHPAASVPK SNLKAPPLDP ANPTPAHSYL
PVPSQSAKLR SSSGSSASGT PTSPPQGSTI TSAAAHSTPQ LQFARFPPTS QNLSESELDP
YFSSFESSSK ELETLLTGSM EKVNARLLRH LYSLGDDLMD LGARYNAFSL SEQSASVAHA
IEKAGQACDF TYIQSRDLSS ALSAGFAEPM REHSQFASVV RSVLKYRVLK RVQEEMTRDE
LEKKKGMLDQ LERSEIEAKR IEQYMSSSGM HSRQQPPQRS TSSGSNRNRP SSQDDNASVD
SDFPPTGGNA PSAQQGAPHE QPYSSSAQSP PDGSHKRASS GVANKIFGRL THAIQGVTDQ
DPERARRDQL GKTKESLVQL EQALEVSQKD VKDASQGVLQ DLRRFQGQKE EDLRTYMLNF
AKSHVEWSKR SLEEWKKAKS EINKIEVR
//
