ID   A0A1X7S8T4_ZYMTR        Unreviewed;       352 AA.
AC   A0A1X7S8T4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Sodium/calcium exchanger membrane region domain-containing protein {ECO:0000259|Pfam:PF01699};
GN   ORFNames=ZT3D7_G11247 {ECO:0000313|EMBL:SMQ56092.1};
OS   Zymoseptoria tritici ST99CH_3D7.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX   NCBI_TaxID=1276538 {ECO:0000313|EMBL:SMQ56092.1, ECO:0000313|Proteomes:UP000215127};
RN   [1] {ECO:0000313|EMBL:SMQ56092.1, ECO:0000313|Proteomes:UP000215127}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC       family. {ECO:0000256|ARBA:ARBA00008170}.
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DR   EMBL; LT853704; SMQ56092.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X7S8T4; -.
DR   STRING; 1276538.A0A1X7S8T4; -.
DR   Proteomes; UP000215127; Chromosome 13.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProt.
DR   GO; GO:0015369; F:calcium:proton antiporter activity; IEA:UniProt.
DR   Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR   InterPro; IPR004713; CaH_exchang.
DR   InterPro; IPR004837; NaCa_Exmemb.
DR   InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR   PANTHER; PTHR31503; VACUOLAR CALCIUM ION TRANSPORTER; 1.
DR   PANTHER; PTHR31503:SF14; VACUOLAR CALCIUM ION TRANSPORTER; 1.
DR   Pfam; PF01699; Na_Ca_ex; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215127};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        202..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          209..344
FT                   /note="Sodium/calcium exchanger membrane region"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
SQ   SEQUENCE   352 AA;  38658 MW;  7E93444B3924C31A CRC64;
     MAIAVSKFRW SPDCVFWLNL VALLPLFGAF RYSTEVLSAA ASPNVGRVWD STLGAFNLDL
     AIAFIGIWRG QLIFAKSYIV GKVVASTLWS TGVCFVASGV RSAESSFDET MSHTLGNLLA
     TAMVPFAILS VFPQTENHPP STSSVLIISR GSSVVFLTIY SFYQLFRHKT HTAFFDPELF
     VDSQDEESSQ QRRRPSSDIR DLGGWVTSVT IIGAATLGYV CSTLALRSMH ESTSLTEEVV
     GFCLIPLLGE ISEITKLSRF AYRDRVDFAL EKAAGLAVQT MLFIGPLLCL FSWSLGQAMT
     FRLDLLELAS LMASIYLFNG ILRDGKSNYL EGALCLGLYA IETLALVVRS RK
//