ID   A0A1X7SPG2_AMPQE        Unreviewed;       579 AA.
AC   A0A1X7SPG2;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=HAT C-terminal dimerisation domain-containing protein {ECO:0000259|Pfam:PF05699};
OS   Amphimedon queenslandica (Sponge).
OC   Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC   Haplosclerida; Niphatidae; Amphimedon.
OX   NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.04000_001, ECO:0000313|Proteomes:UP000007879};
RN   [1] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20686567; DOI=10.1038/nature09201;
RA   Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA   Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA   Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA   Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA   Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA   Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The Amphimedon queenslandica genome and the evolution of animal
RT   complexity.";
RL   Nature 466:720-726(2010).
RN   [2] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA   Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA   Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA   Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA   Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA   Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT   evolution of animal complexity.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.04000_001}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A1X7SPG2; -.
DR   EnsemblMetazoa; Aqu2.1.04000_001; Aqu2.1.04000_001; Aqu2.1.04000.
DR   eggNOG; ENOG502R035; Eukaryota.
DR   InParanoid; A0A1X7SPG2; -.
DR   OMA; ICASPFY; -.
DR   Proteomes; UP000007879; Unassembled WGS sequence.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR008906; HATC_C_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   PANTHER; PTHR46880; RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46880:SF6; TRANSMEMBRANE PROTEIN C17ORF113; 1.
DR   Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT   DOMAIN          494..560
FT                   /note="HAT C-terminal dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF05699"
SQ   SEQUENCE   579 AA;  64573 MW;  AA61ED9BD1FE69B5 CRC64;
     MCYQDQSSTQ HQNCSGSYRE SLHRRAKRRK IDDLIHSEDC LTVDGEAFCD ALRCIYFLAK
     NETPHTTNFV PLHSLCVQLG NTTLPRLLLE GKNRTYPSEQ TMKEMMEAIG SAIEEFLLKN
     ICASPFYSII LDESTDLSTV KQLGLVVQYL DMETATAETK YLKLIDLSPA VHATADVIVK
     AVTAYLEEKA SPAPGLQKLI GAASDGASVM VGRDNGVIVQ LKIKVPGLIA THCSAHRLAL
     AASDAAHTTP WFARFERILN QVYSFFSRSA VHTAELVEIQ RMMDHPKLKL KKPSETRWLS
     LENAVSALRC CYRPVKAVLE NEAAEGDATA LGLHTQLKKP EFIVNIHFLC DVLDTVGSLS
     KAFQSNQVNL LGIENLVKEK LSVLEELQND IYCGGYMLTV IKNYPEELAA VKETNFDTKA
     ACYIKELISS IRNRFPNIRL ITLLGHLHPK HVAEATPAII FELASSLSLN GPNLWNEFMS
     YKSFALSLKP MSLHQSVLEM WHPDRRDTMV AAYPLISQLL AQVIVLPASS AEVERVFSTI
     NRTKTPLRNH LTTMMLDNLI RISMDGPECC EWDPVPAAL
//