ID A0A1X7SW46_AMPQE Unreviewed; 539 AA.
AC A0A1X7SW46;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 28-JUN-2023, entry version 17.
DE RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.06374_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.06374_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR AlphaFoldDB; A0A1X7SW46; -.
DR EnsemblMetazoa; Aqu2.1.06374_001; Aqu2.1.06374_001; Aqu2.1.06374.
DR InParanoid; A0A1X7SW46; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01670; Death; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR Pfam; PF00531; Death; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 426..500
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT COILED 234..328
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 539 AA; 61269 MW; D85126B9D65D2A5A CRC64;
MEEHISGCFT SHPISDACII RKMEAYIKKL DDFMSYSLKD LRSTIEATFD QNNFSSDTAG
IVVIMLNGGW DEMSLNDFES LLKHYFTRRN IFNHLQISPG SVRISYLVPR SAIAHITKVV
KSKSESMRRV GVFYFSINDD VLLDEKDNVD FDKSIIEAVK LDKTFEVSLL LSLRANSQYE
DSNGDKVLEL AIQGGNEEII ELISVATDTQ VMKFKSQEEL TDEEDKETEN NGENETIKLE
IQRLQDLNAE LEKSLAASKS EIDKLQETVS FQKKETEAEL QTCKKQLNAS YLENERLDRV
LEKTRDDSRV LQNKISSLEA NILSLKNEQI INEKILLERT EEIAILQEKL SSLSVQLIDQ
PSRIVPRINK FTQSEAITTM DQSVQSMEIL LPEIDRNQMK IEGMLTIENL IDVLDLLKRC
SFPERRWKEL GLRLGLHKNT LDAITQNHSN VKDCFIECIA RWLSRADNVD SKGGATFDSL
SDALKSMNEN VAADKLDQEK HKAKAIDIFN THHPLLSQSL SDPLSVASKR GCHNRTSIG
//
