ID   A0A1X7SZT4_AMPQE        Unreviewed;       558 AA.
AC   A0A1X7SZT4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Calx-beta domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Amphimedon queenslandica (Sponge).
OC   Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC   Haplosclerida; Niphatidae; Amphimedon.
OX   NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.07668_001, ECO:0000313|Proteomes:UP000007879};
RN   [1] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20686567; DOI=10.1038/nature09201;
RA   Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA   Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA   Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA   Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA   Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA   Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The Amphimedon queenslandica genome and the evolution of animal
RT   complexity.";
RL   Nature 466:720-726(2010).
RN   [2] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA   Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA   Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA   Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA   Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA   Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT   evolution of animal complexity.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.07668_001}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A1X7SZT4; -.
DR   STRING; 400682.A0A1X7SZT4; -.
DR   EnsemblMetazoa; Aqu2.1.07668_001; Aqu2.1.07668_001; Aqu2.1.07668.
DR   eggNOG; KOG1216; Eukaryota.
DR   InParanoid; A0A1X7SZT4; -.
DR   Proteomes; UP000007879; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   Gene3D; 2.60.40.2030; -; 1.
DR   InterPro; IPR038081; CalX-like_sf.
DR   InterPro; IPR003644; Calx_beta.
DR   InterPro; IPR035234; IgGFc-bd_N.
DR   PANTHER; PTHR46534; IGGFC_BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46534:SF1; IGGFC_BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03160; Calx-beta; 1.
DR   Pfam; PF17517; IgGFc_binding; 1.
DR   SUPFAM; SSF141072; CalX-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..558
FT                   /note="Calx-beta domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012462894"
FT   DOMAIN          127..440
FT                   /note="IgGFc-binding protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17517"
FT   DOMAIN          463..552
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|Pfam:PF03160"
SQ   SEQUENCE   558 AA;  61381 MW;  E4C450A6F356B581 CRC64;
     MKRITRILFF LFIILLQQCK GSNLSSHGSE FYLAFPRNVF GATNLTLTVH TLKNASVQYS
     IESLNQGFSY SGTTTAGDPD VVAIPLTYEV YYSSYSYRRL GLHISSLETD PVSVVAWSES
     TYGYFSFLGL PCHTQPTNSY VYYAVSSHGF SNFPGYIILV GCMNNTNVTI APTQYANITM
     PANPQSPISA YKTYRLGENN TFVIHAGQTI RMYQAFADIS GSKIISDAPL TVISGHTAAQ
     IPLGINDADP MATQVTPTIT WGKEFLLSPH HNRNTGQFYK IIAHRPGTNI QRRCGTGLTV
     SATLSSGQVY QFNTSNTSYC SLISNKPIFV AHIGPSTFFN GGTYGDPTLN TVPPISQYLH
     SIEYTRYFAI FSGVNLLIPR DQYFSNNLII DNTLYSITWD ATIYFPNGTI AGYGWYASTS
     GTHTITHAIA SGGISLSIYG WTIYRGYAFS GGMGLDPINP LPQVSFTQEL FIITEGNNDA
     IIYLNRSANV EEEVSVRVSV TPQQLDTAEG GDDYLSTSSV VTFRYGEILH NVTIAIIDDH
     YAEPTEYFTL SLEAVGQD
//