ID A0A1X7T2M8_AMPQE Unreviewed; 527 AA.
AC A0A1X7T2M8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 28-JUN-2023, entry version 14.
DE RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.08714_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.08714_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR AlphaFoldDB; A0A1X7T2M8; -.
DR EnsemblMetazoa; Aqu2.1.08714_001; Aqu2.1.08714_001; Aqu2.1.08714.
DR InParanoid; A0A1X7T2M8; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01670; Death; 1.
DR Gene3D; 2.60.220.30; -; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR Pfam; PF00531; Death; 1.
DR SMART; SM00005; DEATH; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 345..418
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
SQ SEQUENCE 527 AA; 59724 MW; DA0363CDFCA21C52 CRC64;
MKSKIDVRGL VYHCSRTGVT LIIPEEAVQQ PTTVWFGACP FSDKFMLGDF ISITPIVWVH
IDQNLIKPAE LYLPHYINIG AMIEEQLVHM IAGDQSFMDQ GKFEFTVSNN DKMEVNSDLF
KVCCHHFCSH CVAMEKNAYK SSQKHYMLAM AEKQEDKTKF VDFCCFPCQI GCKQLVTKQY
EDIDFKISDT KSFMFNDEGV LSIAFDPDNI PGWDRDQNGF QTEEILESEV DYFKVMGCEA
GNVTKENIEM LKMIEDILSY PPRFRFKFSC LNKALALDAM KVKVVFSGAN KALQISITLE
NPKAFISENL STLQGTPFLT PNITPANDAI LMNLLTVTAD VFHDDHLGSK WFVFGLKLGL
SVSQLHKIEL QYSNPIQFAR ELLLLWRTQN KSASWEPVAA ALKSIELNSV ALKLEGHFRE
QCPIPTLPSS VLEAEPGLPV LNNLVGAKIE DKYHLFGIAV GLNEGYLRGL DKDYATCQER
FHQVFYKWSQ INPDTFKWKT IIEVLQSNTI KATSVAECVI EHLVSIQ
//
