ID A0A1X7T5U2_AMPQE Unreviewed; 400 AA.
AC A0A1X7T5U2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DRBM domain-containing protein {ECO:0000259|PROSITE:PS50137};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.09880_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.09880_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR AlphaFoldDB; A0A1X7T5U2; -.
DR STRING; 400682.A0A1X7T5U2; -.
DR EnsemblMetazoa; Aqu2.1.09880_001; Aqu2.1.09880_001; Aqu2.1.09880.
DR InParanoid; A0A1X7T5U2; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd10845; DSRM_RNAse_III_family; 2.
DR CDD; cd00048; DSRM_SF; 1.
DR Gene3D; 3.30.160.20; -; 3.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR46205; LOQUACIOUS, ISOFORM B; 1.
DR PANTHER; PTHR46205:SF3; LOQUACIOUS, ISOFORM B; 1.
DR Pfam; PF00035; dsrm; 3.
DR SMART; SM00358; DSRM; 3.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 3.
DR PROSITE; PS50137; DS_RBD; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 4..77
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 98..172
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 199..273
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 79..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 44426 MW; AB2268B7CD842BA8 CRC64;
MASNAMVDLN GYCTKNRLKI EENYEYTGPS HYRLYVCTLT VRGQDSGRVP VTGRGEGKNK
KEAKMKAAQD IMTKITDEEV EATDSEAVPS PKTPEGPNYK VHLQEYCQKK GLGIPSYSVL
RTTGPAHQLQ FEIKCTVYRC YEELIGEGVG VGNSKKVAEI EAAKKVFDFL KTENPQHETI
ALTPGETETP PPSPLVEGNN KNKLQELCQR NGFEIPKYIK ISQTGPSHSM DYTVKCCVMD
SEDELVAEDK GFGKTVKSAE MEAAGKVIEK LTKVLHLLEK LEEGEKVEHL DLSVMKTLRV
DREESMEYAS IEDLTDIIMS YNCSTPQFIV QKTDPVDKDD PSTMQYLCLA HSTGGEGFIN
NTGYDTSKMP IVGHGSSPLE EDAKKLALND LLHNIKQLQA
//
