ID A0A1X7TE42_AMPQE Unreviewed; 634 AA.
AC A0A1X7TE42;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.12615_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.12615_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR AlphaFoldDB; A0A1X7TE42; -.
DR STRING; 400682.A0A1X7TE42; -.
DR EnsemblMetazoa; Aqu2.1.12615_001; Aqu2.1.12615_001; Aqu2.1.12615.
DR InParanoid; A0A1X7TE42; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01670; Death; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 40..115
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT DOMAIN 501..562
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT COILED 454..481
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 634 AA; 72277 MW; 1972B7D38F30262F CRC64;
MATKTSSCSS SLSLFSSPLT INQLIDVLDL LKRCGFPQTR WHELGLRLGL HKDTLDVLEA
IFSRDVSRCL IETLSKWLRR ADNVDSKGGA TFDSLSDALK SMNENAAADK LDQESKIAVM
TAVVRHVTSS TVNQLPTANT PVSAGEFFFN AAYRPVFNEV RGHFGILRDK IVPLISQSKA
SIEEMKSFLQ KSFPELGPDL SNADSIEDIM NVVVKNCRVN DISIIKTIVL RFDITEADDL
ISKYEGKVKT LTGSLKDFLS LNEPQHLNDS NTIQFTLGWE PDEHSLDDIR NLLEEAFKEL
NKRIIVRSIH RGNSIIIICY GPHHLLAALL LEAQDNLTVL MKEFSLIRLT ISHYTVYDKR
IRYKVMNNEC LAEEIKLADG EEQELRTELD YKEGSIFEQD KQLNIIKKRK EYIERRLETP
ESKLKLLTRG KLINKIFKSK KSETQYFRTS LLMKAGREEA LVEYKKEIEL LQENISITSV
QLLMRETGNI EKKDQCTQSP TAESIYTARF DYHGIWRGDL SFSEGEQLKI YDNSDSFEWK
GRSLVSGDEG IIPSSCVYSM LESLQLLEFI LSVEEVSLPI LQKIRNDSSS NDEKASLFLE
TINDDPIMIP ALRQDKEQHD KGNICDYCDS QYNY
//
