ID   A0A1X7TN73_AMPQE        Unreviewed;       405 AA.
AC   A0A1X7TN73;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
OS   Amphimedon queenslandica (Sponge).
OC   Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC   Haplosclerida; Niphatidae; Amphimedon.
OX   NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.16245_001, ECO:0000313|Proteomes:UP000007879};
RN   [1] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20686567; DOI=10.1038/nature09201;
RA   Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA   Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA   Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA   Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA   Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA   Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The Amphimedon queenslandica genome and the evolution of animal
RT   complexity.";
RL   Nature 466:720-726(2010).
RN   [2] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA   Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA   Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA   Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA   Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA   Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT   evolution of animal complexity.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.16245_001}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A1X7TN73; -.
DR   EnsemblMetazoa; Aqu2.1.16245_001; Aqu2.1.16245_001; Aqu2.1.16245.
DR   InParanoid; A0A1X7TN73; -.
DR   Proteomes; UP000007879; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   Pfam; PF00531; Death; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT   DOMAIN          40..114
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
SQ   SEQUENCE   405 AA;  44854 MW;  AAD38EB16CBDC8C0 CRC64;
     MATKTSSCSS SLSLFSSPLT IEQLIDVLNL LKRCGFPQRR WKELGLTLGL LMDSLDAISE
     NCSKVEDRFI ECIARWLRRA DNVDSKGGAT FDSLSDALKS MNENAAADKL DQEKRKAKAI
     DIFNTHHPLL SQSLSDPVSV AIMLQREGVI TGQVLASVES ASPSVPNQRE VLLGAIIVAI
     ESKYSLLQTF ASVLCKFTGN VKLGTVIQRD YDTQFSTDEF VNIEMEEDSS TGTITPSSPH
     TPTAPLTVEI PVRKSKSREF SSIRASLARM IFKVSKAITQ KSPPLFDLKS LICLFNSDLK
     GKLAECNDIS SVVHVIEGEC SLTDIELLET VVEEFEVTEA ERYIEQYKTS LEKSCHSLSI
     DLCLKEKFDA VNTSPSLKCE SATFVFDWRP DEKKLKDITD ILSKT
//