ID A0A1X7TRX5_AMPQE Unreviewed; 590 AA.
AC A0A1X7TRX5;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=MCM domain-containing protein {ECO:0000259|Pfam:PF00493};
GN Name=105314482 {ECO:0000313|EnsemblMetazoa:Aqu2.1.17598_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.17598_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.17598_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019858141.1; XM_020002582.1.
DR AlphaFoldDB; A0A1X7TRX5; -.
DR STRING; 400682.A0A1X7TRX5; -.
DR EnsemblMetazoa; Aqu2.1.17598_001; Aqu2.1.17598_001; Aqu2.1.17598.
DR GeneID; 105314482; -.
DR KEGG; aqu:105314482; -.
DR InParanoid; A0A1X7TRX5; -.
DR OrthoDB; 5294704at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF75; MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00493; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 244..362
FT /note="MCM"
FT /evidence="ECO:0000259|Pfam:PF00493"
SQ SEQUENCE 590 AA; 65946 MW; E74498C339A2B13B CRC64;
MEWLPATTLA SPNQLLLLIR LSSLPAFPPY HVSHVCELQS PMDEGEGQFI SCTGIVTSIT
NIEKYTESAC YYCPNSSCTS DPHIRYHSVG SYEYNTINDN LKCHYCGLIL IEDVKQRILS
DKLLISLVPT DVLYPVSGSS YQGFTVILRD DLCSMVEIGG EYTVIGVAIN NNSTNNGRIT
VDTVIEANNV YKTLNDSTNK QLSPNILQIF NGCQYSRWSF PAILAYYFAS DVVPPGLYHR
LKLIILLSLV ACSEPRNRMI DVLLIIDNDS QYIARQLLTY SSTVTNNRSS AVTNNRSVIH
TVNGGVHLNG TIRRDEGLEW IDAGSLILSK GGVCFIDNIN SMKKDEKEQL QQVLESGYIT
IHSNRKSVSS SSLTVPLNCT LWLLCDSNLN TDHVMHKPLH ELSGTCASKS LMDHSGLLLL
VDSSDDYVDQ IMSTHLINKV TRDRSLSTHP HPLLTNDEII EILSFCSSID VTIQSDAHQL
LTSYYVASRR LRGSDTPLTA LNTLISLSVS HAKLNLQTKA TVNDSLLSIL IYEQSLIHRY
GHSALYIKPF LHFKEQDSIN NFDHYMKEFS VQVHSFIDSH SSNVHIQTEE
//
