ID A0A1X7TZ02_AMPQE Unreviewed; 514 AA.
AC A0A1X7TZ02;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=UDP-glucuronosyltransferase {ECO:0008006|Google:ProtNLM};
GN Name=105314183 {ECO:0000313|EnsemblMetazoa:Aqu2.1.20496_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.20496_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.20496_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_011406490.1; XM_011408188.2.
DR AlphaFoldDB; A0A1X7TZ02; -.
DR STRING; 400682.A0A1X7TZ02; -.
DR EnsemblMetazoa; Aqu2.1.20496_001; Aqu2.1.20496_001; Aqu2.1.20496.
DR GeneID; 105314183; -.
DR KEGG; aqu:105314183; -.
DR eggNOG; KOG1192; Eukaryota.
DR InParanoid; A0A1X7TZ02; -.
DR OMA; MANEACM; -.
DR OrthoDB; 382054at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF145; EG:EG0003.4 PROTEIN-RELATED; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..514
FT /note="UDP-glucuronosyltransferase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010882049"
FT TRANSMEM 477..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 514 AA; 57980 MW; 5999060DAA37FBDC CRC64;
MVGCLLLLLF ACLCSSSSLD VLLVSAPFPG HANRLLAIGE ELVVRGHNVT FSSLDNWVNL
RHKSTERGIR YLSAGKQTVT QAEWNNIISK RASLQGFFSK NPLAIIEELR LLDQSRPLSG
IDEIAKYFMN INLKQWDIIV TEHYLLHRIP CIAKSRDVTV VITSMTYFSN ESPPWPFPVY
QSGYSDNLSF KERAVIGLST IGWRCLSAFS LHWVLIQSPV TESLCKETFK YPVELGWEVP
YIIMTVLGLE YPRTISPLTT YVGPVLSQAL LNQHSLPVDL NDWLRNKNNK SVIYISMGSQ
LSLSDKIAQE IVNGISDTDY HVIWSVGDIN KDIILNIDSS RYYTSSWIPQ VTLLQHSSIS
MAILHGGSNG IHESLYFGIP IIVIPGMGDQ FDWAVRVSDA GVGLQLLRHE VTSRGLRDSI
RRIDNDGYHK RAEKMSVLMK RGGGVKRAAE LVEFYGTYGY DHLIPGPIKY KWNWIQYYNV
DVYIVLLVGL VAIVMILKRS CKCCTAKKTK TKQN
//
