ID   A0A1X7U017_AMPQE        Unreviewed;       312 AA.
AC   A0A1X7U017;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   28-JUN-2023, entry version 16.
DE   RecName: Full=C2 DOCK-type domain-containing protein {ECO:0000259|PROSITE:PS51650};
OS   Amphimedon queenslandica (Sponge).
OC   Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC   Haplosclerida; Niphatidae; Amphimedon.
OX   NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.21116_001, ECO:0000313|Proteomes:UP000007879};
RN   [1] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20686567; DOI=10.1038/nature09201;
RA   Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA   Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA   Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA   Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA   Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA   Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The Amphimedon queenslandica genome and the evolution of animal
RT   complexity.";
RL   Nature 466:720-726(2010).
RN   [2] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA   Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA   Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA   Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA   Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA   Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT   evolution of animal complexity.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.21116_001}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00983}.
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DR   AlphaFoldDB; A0A1X7U017; -.
DR   EnsemblMetazoa; Aqu2.1.21116_001; Aqu2.1.21116_001; Aqu2.1.21116.
DR   InParanoid; A0A1X7U017; -.
DR   Proteomes; UP000007879; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR027007; C2_DOCK-type_domain.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR026791; DOCK.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF26; ZIZIMIN, ISOFORM K; 1.
DR   Pfam; PF14429; DOCK-C2; 1.
DR   PROSITE; PS51650; C2_DOCK; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT   DOMAIN          160..312
FT                   /note="C2 DOCK-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51650"
SQ   SEQUENCE   312 AA;  35183 MW;  470E274A53930EC8 CRC64;
     MFTSAASLVL YPRTFCIPGS RKMKEQHELA MLIVKEALPE EFIALPLFLS EDEVNVHCTD
     LGPIYRQERE KLTDTELIKI LSDFKNIGRH KLQTIPGSLN VSIIGSATPG VIFTPSYLPV
     KSTVPRQLTP DTQASLEVRE FLSLDSYDSF SHCSPHISHI NHFYVYPVSL KYDTQKSFPK
     ARNIAVTIEV RDNDTDRYTR PLKVIYSKSS SDELLVDSVT TPVLYHCTYP SFYDEIKIQL
     PTRINRRHHL LFTFKHISCD IQKIAKGGGA SGRGSVKHNS IETIVGYSWL PLLGNDGRIN
     SESLLFTSVS SC
//