ID A0A1X7U025_AMPQE Unreviewed; 844 AA.
AC A0A1X7U025;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DDHD domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100633695 {ECO:0000313|EnsemblMetazoa:Aqu2.1.20846_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.20846_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.20846_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019856834.1; XM_020001275.1.
DR AlphaFoldDB; A0A1X7U025; -.
DR STRING; 400682.A0A1X7U025; -.
DR EnsemblMetazoa; Aqu2.1.20846_001; Aqu2.1.20846_001; Aqu2.1.20846.
DR GeneID; 100633695; -.
DR KEGG; aqu:100633695; -.
DR eggNOG; KOG2308; Eukaryota.
DR InParanoid; A0A1X7U025; -.
DR OrthoDB; 1365902at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004177; DDHD_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR004170; WWE-dom.
DR PANTHER; PTHR23509:SF45; LD21067P; 1.
DR PANTHER; PTHR23509; PA-PL1 PHOSPHOLIPASE FAMILY; 1.
DR Pfam; PF02862; DDHD; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF02825; WWE; 1.
DR SMART; SM01127; DDHD; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS51043; DDHD; 1.
DR PROSITE; PS50918; WWE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 242..325
FT /note="WWE"
FT /evidence="ECO:0000259|PROSITE:PS50918"
FT DOMAIN 738..844
FT /note="DDHD"
FT /evidence="ECO:0000259|PROSITE:PS51043"
FT REGION 43..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 674..702
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 54..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 92619 MW; 5028225208805D97 CRC64;
MSVSNTPSKE KASLFNADLF SSPATGLSSL GFGDDIFSGG SPFTLAPAAP AVPSVATPSS
NEGGGATPPS KSDETLHTVP LDSPTLAEEE DSRRGQTTSL PLLSVPGSVA GWNDPPFLSS
LSAPPPPSRT VSTPLSGGDF HVQPLVDNRR SESPRPSPAP PTGSSNPYRL GVGGAASSKR
PVYTQNMIPP TSGSQAPPIA PPTTGPLTYA PPTNPQIVAP PTYSQAPPTY SQAPPTQSQA
PSLTVEKPSI IPVQAHWFYL KEGQEYWYPF SLIDSSKLEE IYIRLETDPS FNSVVQTDGG
RYDVDVSKRQ RAAVYWDEPP GLVRRCTWFY KGDDDRWYKP YIEDIAIKLE TAFTEAVMQG
NWNCRVDLPE GEAVVINSPT AIAHYPAHQV QTLNYEIDYK PKAVLRGFLE RDKVQMGEDK
NIDHLVFVVH GIGPFADIRL DSFRSLIDCV DDFREVSLLL LRSHDVSGRG AGGQGRVEFL
PVQWHSALHG DDTGVDKQVK SISLPSISKL RDFTNSTLID ILFYTSPLYL QTIIDQVSSE
MNRMYALFKE RNPSFSGSVG VMGHSLGSCI LFDLLYHQKV DGGVSMGVVK DPVPQSLPVT
ESTDSLEKQE EKEKEEEEDA PAVSDILNQL GLPQLIEKFE SEMIDFNTFI LCNNEDLKEI
GVPLGGRKKI TSYIDEWNKK KEQEQERKVK EAEERLREEE LKKSLAADGA CVGGVTETVT
YVKGTAGTGQ PLVNYPLLNF NPSSLFAVGS PIGLFLTLRG VESLGPEYQL PTCSSVYNIF
HPYDPVAYRL EPLLVSQAPL KAALLPHHKG RKRFHLELYE NIERVGQSVK YHLVEGIRNM
GISE
//
