ID A0A1X7U1Q7_AMPQE Unreviewed; 534 AA.
AC A0A1X7U1Q7;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000256|PIRNR:PIRNR017300};
GN Name=100640932 {ECO:0000313|EnsemblMetazoa:Aqu2.1.21797_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.21797_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.21797_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC {ECO:0000256|PIRNR:PIRNR017300}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR017300}.
CC -!- SIMILARITY: Belongs to the MPP10 family.
CC {ECO:0000256|ARBA:ARBA00029455, ECO:0000256|PIRNR:PIRNR017300}.
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DR RefSeq; XP_003389197.1; XM_003389149.2.
DR AlphaFoldDB; A0A1X7U1Q7; -.
DR STRING; 400682.A0A1X7U1Q7; -.
DR EnsemblMetazoa; Aqu2.1.21797_001; Aqu2.1.21797_001; Aqu2.1.21797.
DR GeneID; 100640932; -.
DR KEGG; aqu:100640932; -.
DR eggNOG; KOG2600; Eukaryota.
DR InParanoid; A0A1X7U1Q7; -.
DR OrthoDB; 181024at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0034457; C:Mpp10 complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR012173; Mpp10.
DR PANTHER; PTHR17039; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR PANTHER; PTHR17039:SF0; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR Pfam; PF04006; Mpp10; 2.
DR PIRSF; PIRSF017300; snoRNP_Mpp10; 3.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017300};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|PIRNR:PIRNR017300};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|PIRNR:PIRNR017300};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|PIRNR:PIRNR017300}.
FT REGION 95..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..144
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..206
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..469
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 60777 MW; 726A8175FA954897 CRC64;
MSLSSLSSLL SKQPIEFISS SPELKELCLS SLKESFAQVV GSVESSVKER PCVQELHTEG
FGLVDIWEQL ELVNDPLLKH LKKHLKTNVN HFLSEVDDNN NKTSEADDIR SDNEEMIEEE
EEEEELLSED EGIEEMDSED PESDVASVGG EVGGDSDQFF DLNKMEEFLK EAEKMDEGSD
EDDIDLFDSD AGEGSNDEEE QEEEDEDAKR SLYQYYDDFF DPAPSSTTKT PSVDQPLSLH
QKKQEKMKSY IAKLEATNIA EKPWQMTGEV TSKGRGENTL LEEDLMFKDA SRPAPEITEE
VTLTLEEIIK QRIKDQAWDD VIRKTKPKER PFNYKVFQPL NEEKSQLSLA EVYEQEYIKQ
TQGEREEEEN PKHKEIRELV KKLFNQLDSL SNYHFTPTIA EPEVKSIPLL PSISMEEVAP
ITHSETTLRA PEEIETPSQV APVGETERSS TDKKRQRRHK KKRQHAIALS KEKKKALKAL
SVKLKKTSAT RSSNRFFAGL EKEAKVSLKK EKSKLTNKLI NLGNTTHTSS GLKL
//
