ID   A0A1X7U2B5_AMPQE        Unreviewed;       997 AA.
AC   A0A1X7U2B5;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   28-JUN-2023, entry version 14.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Amphimedon queenslandica (Sponge).
OC   Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC   Haplosclerida; Niphatidae; Amphimedon.
OX   NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.21903_001, ECO:0000313|Proteomes:UP000007879};
RN   [1] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20686567; DOI=10.1038/nature09201;
RA   Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA   Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA   Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA   Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA   Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA   Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The Amphimedon queenslandica genome and the evolution of animal
RT   complexity.";
RL   Nature 466:720-726(2010).
RN   [2] {ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA   Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA   Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA   Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA   Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA   Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT   evolution of animal complexity.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.21903_001}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A1X7U2B5; -.
DR   EnsemblMetazoa; Aqu2.1.21903_001; Aqu2.1.21903_001; Aqu2.1.21903.
DR   InParanoid; A0A1X7U2B5; -.
DR   Proteomes; UP000007879; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46844; SLR5058 PROTEIN; 1.
DR   PANTHER; PTHR46844:SF1; SLR5058 PROTEIN; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT   DOMAIN          298..418
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   997 AA;  113515 MW;  2123730774B6642B CRC64;
     MILLTDNCYQ VQCTTSVTVT DTNYLQSVVL PGGSSSNLIY NDLYLIVCLH MLLLLSGDVE
     CNPGPITGNT PSALLRMNYA TLVDAIANNL HRVTNGLYAK GLIPMETVNH IQTANAISDI
     VKSGQLMSVL QRQLEASSTP EQFLTDVCHI LINQQHCILT DIATSILHQL GQLDLVNVSS
     HTALPSPLHD ESKAPVTNRR GLSDVAKIAS IPDDVQGYAD NMKQHYKHQP IVATDWPPRI
     EKNFFGRLAL IEKQDSSTQA ESAWHMLRGQ VDKTVKLTEN KEISVEDVLQ PTDSSLSLRI
     VIDGPPGIGK TTLCRKLLNM WSNGPLPHQQ YNLVLYCPLR NSKIATATTL AELFVRQRYE
     VPMVAEWFEK RNGEGLLIIF DGWDELSEQL RQSSLAASII CKDQLDQCSV IVTSRSYASF
     SLLELDNLSR HVQVIGFSED EISTVIIQTL QKDPKLAQEI INENTEKELI SKRKYKSFFT
     TTQACKDSKL AVKLINDLEL RNDVQSLCYV PLVCSMVILV YCKEGGHLPK TLTELYENFI
     LQTIRRHFKR HDINPRTLGS LSSLPSQLAK PLQEMCKLAY TNLANTRMTF SSHQLQSLSD
     AVKEDYLGLI TTFMDYDEEK YQFLHLSIQE FLAAWWIAKH EEKTEEVFKD HFDDDHFRMC
     LRFVAGLTHL EHESYQQYFN KQLLDLQCKR EPLFHFETCH LSYFHQNPEI PQKRHISSDD
     FDNIPNLLFQ LLYESQNTTL CQVLAQSINN HSLCLNMVDL SLFDWLCLSY CINNINITWN
     HLHLGKVRNQ SLTVFTELMN KSLQSQCKRL EVELYEPSIE LLNNLLQQSL FYNIQECYCT
     STVCQYIVLI QFLKLPQLKV LHLIMGRSAV DSSCTDKCTE LEKCIEMNSV LQEMKLGGGE
     RREVIISVMK GVSQNKTIKS FSLDIDVFAH RLTLLDGLIE QLLKDNTTIQ ALSLNIPDVL
     LQSRLTYYIL EVNTPLTALE IGQSNYELME SLLPPTR
//