ID A0A1X7U3N7_AMPQE Unreviewed; 949 AA.
AC A0A1X7U3N7;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Sushi domain-containing protein {ECO:0000259|PROSITE:PS50923};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.22149_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.22149_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR AlphaFoldDB; A0A1X7U3N7; -.
DR EnsemblMetazoa; Aqu2.1.22149_001; Aqu2.1.22149_001; Aqu2.1.22149.
DR InParanoid; A0A1X7U3N7; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR CDD; cd00033; CCP; 7.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 8.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF573; SUSHI DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00084; Sushi; 8.
DR SMART; SM00032; CCP; 8.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 8.
DR PROSITE; PS50923; SUSHI; 8.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 2..57
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 59..116
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 117..174
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 175..232
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 233..290
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 291..348
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 349..406
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 409..464
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 497..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 87..114
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 145..172
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 203..230
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 261..288
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 319..346
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 377..404
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 949 AA; 101924 MW; 1A7381DB9BF5577D CRC64;
VVDCGTPPSV LNASHSQLDG DTQYGARVQY NCSTGFNING NDTISCLLNA SWSLPTPSCY
CSNPGEPANG YTNDNVFTYQ STVQYHCNEG YQLSGDSSIE CTANGNWNNT LPNCVIINCT
DPGTPTNGTR NGMDIYYNST VSYSCNTGYN LTGAASITCL ATGLWSAPVP SCPPVNCGDP
GIPTNGNKSS SVYTYNSVVF FQCSSGYFLS GPVSLICLLN GSWNDTAPTC NPVNCGDPGT
PTNGTRNGTV FTFNSTVLYL CDTGYTITGA TSLTCLSNGL WDASVPSCDI VNCSDPGEPT
NGMLQGGTFT YNSVVTYNCS VGYNLTGATS LTCLADGSWS ASVPSCPPVN CGDPGTPING
SKSSSVYTYS SVVSYQCISE YSISGADTLS CLSTGLWNGS APYCYPDCID PGNPSNGQRT
GDTFNYNSVL SYTCNTGYNL TGESSITCLS NGTWINCSDP GTPTNGEGLG IYSHMELRWF
IALLQFRRAF TSSSEVSTLS QTTTSSMQRS SSLSSLVNPP STTQPTLSMS SATTLSTSST
VMPTTSADDI SKSRRKSRKL NVPATTNLTS PILFSNLYNS MSKDSKAAPS EEHPVPDYDD
PALTLKHETT PQTFTNLLYS ELEALKTEDD NKYPTEDYDN ENIANVVLPP PIYLDVDDDT
KGVANSLYFI QEEAEEKDEG GAGAVYFTLD EDAATESGDK KDLPVYFTLE NERKTVPKFN
ARKLAKRNTI AFVQPGESED EIYGQIERSS NPMIHRDSLI LSTIIGSGQF GNVCKGQWKK
TNGDTIDVAV GNDASLSIYR ETFPGGKWFL STLSPATCSR SFYDYNISFY TSSLNIGSTY
NVTLAIWKQV GSKTYEKDPA TIQHYTYTHT NNRRKKRATL NTAPFSSAVG IRKGSFVGAY
LYTTANALPI TGIRYTSRIG ACVSKNSASA TTITCSFNHY YVVHAEADV
//
