ID A0A1X7U6Z3_AMPQE Unreviewed; 819 AA.
AC A0A1X7U6Z3;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Tubulin-specific chaperone E {ECO:0000256|ARBA:ARBA00015004};
DE AltName: Full=Tubulin-folding cofactor E {ECO:0000256|ARBA:ARBA00030180};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.23226_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.23226_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR AlphaFoldDB; A0A1X7U6Z3; -.
DR STRING; 400682.A0A1X7U6Z3; -.
DR EnsemblMetazoa; Aqu2.1.23226_001; Aqu2.1.23226_001; Aqu2.1.23226.
DR InParanoid; A0A1X7U6Z3; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF250; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 3; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 25..69
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 404..646
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 819 AA; 92785 MW; 9D2B92490BD78BC4 CRC64;
MASDQEVGKR CLSNDGYFGT VRFIGQVPPT KGEWLGVEWD DPSRGKHSGT HDGIEYFRCR
IPNSGSFVRP DKVSLGLDFV QVITERYTYS IDSTGENVLE RVSTKDVLLI AGKETQSELK
ELVNVDLSLT LLSTSGVPQG ILNTCPNIRC LNLSSTLISS WNEVALICSQ LHLLTTIDLS
SNRMTTPTDP LSLLDSLKNV THLIINKMGL EWNDLRLILQ MMANLKQLVA SNNNICCLGN
GGDSKDAFPE SIEEICLDYN KINNWLEVIK LRHLPKLNAL FLRSNQLINI EPINKGDFFS
LISLVLNDNP FESWCSVDAV ASIENLRKLR LIKSPIFKDE SELDARLLVI ARVPQITYIN
GCQIYKKERE NAEMFYIKKY FPEWIKAKKS GGEACFLSNH KQYKRLSEIH GLPEEESIAK
ESPFAPTIKD RLLNLTILDV ASSKTIKRKL PETMTVQELK SLCMRFFKVK TINQKLYYRS
HELHLAQQHM GYCPQFDSLI ELMTGRELLT MFARLKGIKE KLIPKEVEAE IERMNLKQYA
DKRCGTYSGG NKRKLSTAIA LVGQPPVVFL DEPTSGMDPV TRRFVWNAIT GIIKEGRTVI
LTTHSMEECE ALCTRLTIMV NGSLKALGSV QHLKSRFTSG YLLQLKVDSA RRTSDRPKEN
KTIRQRFTKK LSRAFSFEKR TCRSEEGTEE LETFNSQESN TRTTAANAWG RVTVLTRVTN
RIQKLVSRRA SEDSSNIEDS PLEKATKRAS SAIINLFPKA TVIEKYLGSL TFEVPKDGAC
LSELFEKIEQ IKRDIGIIDY SISQPTLEKV FLRFAKQQD
//
