ID A0A1X7UA76_AMPQE Unreviewed; 826 AA.
AC A0A1X7UA76;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=MACPF domain-containing protein {ECO:0000259|PROSITE:PS51412};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.24563_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.24563_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR EnsemblMetazoa; Aqu2.1.24563_001; Aqu2.1.24563_001; Aqu2.1.24563.
DR eggNOG; ENOG502QRKR; Eukaryota.
DR InParanoid; A0A1X7UA76; -.
DR OMA; FHANLED; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd22579; MPEG1_P2; 1.
DR InterPro; IPR020864; MACPF.
DR InterPro; IPR039707; MPEG1.
DR PANTHER; PTHR31463:SF1; EPG-6; 1.
DR PANTHER; PTHR31463; MACROPHAGE-EXPRESSED GENE 1 PROTEIN; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
DR PROSITE; PS51412; MACPF_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..826
FT /note="MACPF domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010889196"
FT TRANSMEM 763..788
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..355
FT /note="MACPF"
FT /evidence="ECO:0000259|PROSITE:PS51412"
FT REGION 268..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 826 AA; 92347 MW; 1915C6694C96910A CRC64;
MRDFIAASFV LLSIFLIHGA SSSYPVGDIR NCPTEQTVNP GSPLLRMDAM PGLGFDNLRN
IELGQVYSRN YSSCQISNDG RYLLPDNINL IPVLKSEIDT SAEVFSHYNE YTSSSSHSIN
VEASASYGCA HASGKFSMEH QDTKKKMASS KSSSVRIGIR HHLYSVHVNP DSQLHPSFKS
RLMDLAAHIQ NNDTQMAHYL SDLIVRDYGT HVVTSVETGG ALYQTSFVSQ DVIENSQYLK
SSVEIGASVG AKFIATFSIS TNIGWSNSNG EKEINSDSNH HVRTSTHGGP PFKMENFSYT
DWQNGLLNNL VAIDRRGQPL SFAMTTANLP ELPDMLLTKT SDYIYKSIER YYKTNTIKGC
TKMDSKNFNF HANLEDNSCX XXXQILPELP DMLLTKTSDY IYKSIERYYK TNTIKGCTKM
DSKNFNFHAN LEDNSCEKDR QNFTFGGIYQ TCEDHDNNEI CNDYGASQKN PLTSDYSCPD
GYESILLHTG TLSKMVQVTY YYQKKHCKFI FDCKMQPASS QRSEMRYSTY NAYWCYAPPG
KQEGADSGYM FGGLYTSKTP NPVTRTTTCP PFYNTLHFGE DIKVCVSTDD QAKDYAIPFG
GFHSCKSGNP LAITPDMYQK LASNNLLEYG SSFPTECSHH YNQFLVTIDE GCVVNYCSQF
QDIIQFSPRP PLVPPYKMKP PMTVNKTESL VIFGPYGKIW VKNDDGSWFE YKNDSVSGPD
YFQSLFVKED DIAIPTELPP TNATVSDDTT SSPSHSYYTG GEVAGIVIGS IFSTALCVAF
IAAVGCGVKK YKKKRIARKE AVLYLDKSET GENETAVLVQ KLQDQD
//
