ID A0A1X7UAT9_AMPQE Unreviewed; 549 AA.
AC A0A1X7UAT9;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DED domain-containing protein {ECO:0000259|PROSITE:PS50168};
GN Name=109584098 {ECO:0000313|EnsemblMetazoa:Aqu2.1.24880_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.24880_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.24880_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019855247.1; XM_019999688.1.
DR AlphaFoldDB; A0A1X7UAT9; -.
DR STRING; 400682.A0A1X7UAT9; -.
DR EnsemblMetazoa; Aqu2.1.24880_001; Aqu2.1.24880_001; Aqu2.1.24880.
DR GeneID; 109584098; -.
DR KEGG; aqu:109584098; -.
DR InParanoid; A0A1X7UAT9; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001875; DED_dom.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50168; DED; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 29..110
FT /note="DED"
FT /evidence="ECO:0000259|PROSITE:PS50168"
FT REGION 246..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 305..368
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 481..528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 62175 MW; B784B8BE12D24C70 CRC64;
MATHHQSEQG DEMYWPTTPR SKDAELYKDY KKLLAGIAEE MQKADVIALA YMFDLPKWYS
EVGATKETSY AARVLSFIEG RNIISPDSLG PLATSLEEIG RMDLKRKIDA FENRHRNRVM
KKPTEETCAN ISDKIDEEEE DYEQFGRVDA RRSYNQRRRN VVRSSSDRYP SSMWLSAPYK
TTSITGTIPV TQQYTTGGSY MPNRPIIHSP PSFSSPPPQS DLDSMEVHVS MESDMHQVND
PRQKYIQPQS ASRKNEHRIW GSMPPKDRDN RSERTLFKLE QFDSVPQPSP SQHLDPDARS
IHLSIRTTTM TAKALKKQIE FLRERLGGSY PYLDKQLQQA DNCTKETLDV LKLLARETRN
QSREEEEEED VLLYKGTTHQ RNPAQRHKRY YSEGFHEGAP PVAFQRCNTQ PEGTGYKISL
SIDESDLDDE IQSPTGVSDE LPEDIVSVEA VISPEFVSSK SRKVSAPVRS PPPPLVTSSA
RLSVKAESIG NINKTDGAST HSGRAKGKQK ISVQPSKSMS SLDEASPAKQ STGKKKMWPL
KIFRSQKNL
//
