ID A0A1X7UFZ2_AMPQE Unreviewed; 610 AA.
AC A0A1X7UFZ2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Receptor ligand binding region domain-containing protein {ECO:0000259|Pfam:PF01094};
GN Name=109583448 {ECO:0000313|EnsemblMetazoa:Aqu2.1.26884_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.26884_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.26884_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019854361.1; XM_019998802.1.
DR AlphaFoldDB; A0A1X7UFZ2; -.
DR EnsemblMetazoa; Aqu2.1.26884_001; Aqu2.1.26884_001; Aqu2.1.26884.
DR GeneID; 109583448; -.
DR KEGG; aqu:109583448; -.
DR eggNOG; ENOG502SRW4; Eukaryota.
DR InParanoid; A0A1X7UFZ2; -.
DR OMA; RHERSMI; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30483; LEUCINE-SPECIFIC-BINDING PROTEIN; 1.
DR PANTHER; PTHR30483:SF6; PERIPLASMIC BINDING PROTEIN OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..610
FT /note="Receptor ligand binding region domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010883202"
FT DOMAIN 89..291
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
SQ SEQUENCE 610 AA; 67235 MW; F474027B51F23EBE CRC64;
MKYFSVAIFF IALTYASCAQ FGYEGYRVEE SEDFFSDIMG DDLTVGALVP LSGHASHVGR
IVRASFMKSS QDLSRSCKGS CRAPRVRSYN THSNPASAVQ GFKEMYEEGV RVFIGLVTSA
EAEAVAKHAS MYAKDAILIS PTSTATNLCK YKQLYRLSMD DRGYAQVLFD LAFDAKTKNA
RELPIQMVLR NDAHGKGLFN DVHQKFENKD GFKVLNPIFY DTDQVLTSSH FGQLVNHLNA
SLARHERSMI VFSGYGEVEG IIQTAAKNPN LLRHLWLLSD SLTLSKIETP QNVDIFGLSF
AGNYDSESDT KKEEHKLRHY LCSKGLPLTK HALLAYDAII VAHNYLIRKS FSSFQDGKTF
TGAIKFSSCN ERASGSYAFA IAPREKKIDN LLVKVIMNKW IIRSYYNVKQ NEREILASQY
EELNNEAKIE ADLQSSTKKS ITATDPPVIE IKKKDLLEVL VDIGDKRCTQ TAQLTTTSIE
VLDKTCSQTK LSYKVMEMPE AIIFSDQLGF SMEVTCSSAN YVHTLTRVCP SSKSPDTELV
CTDKVSSKAI GKVEVEDACT GSKIGTGVCY TGAAGCWVST FFTWGVTAPA CSAATAGCSA
VSAGSYLACN
//
