ID A0A1X7UG80_AMPQE Unreviewed; 911 AA.
AC A0A1X7UG80;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100637383 {ECO:0000313|EnsemblMetazoa:Aqu2.1.26974_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.26974_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.26974_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019854260.1; XM_019998701.1.
DR AlphaFoldDB; A0A1X7UG80; -.
DR STRING; 400682.A0A1X7UG80; -.
DR EnsemblMetazoa; Aqu2.1.26974_001; Aqu2.1.26974_001; Aqu2.1.26974.
DR GeneID; 100637383; -.
DR KEGG; aqu:100637383; -.
DR eggNOG; KOG0035; Eukaryota.
DR InParanoid; A0A1X7UG80; -.
DR OMA; NKECAIS; -.
DR OrthoDB; 2881296at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR CDD; cd21198; CH_EHBP; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR022735; bMERB_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR019448; NT-C2.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF62; EPS15 HOMOLOGY DOMAIN CONTAINING PROTEIN-BINDING PROTEIN 1, ISOFORM F; 1.
DR Pfam; PF12130; bMERB_dom; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF10358; NT-C2; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM01203; DUF3585; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS51848; BMERB; 1.
DR PROSITE; PS51840; C2_NT; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 7..158
FT /note="C2 NT-type"
FT /evidence="ECO:0000259|PROSITE:PS51840"
FT DOMAIN 213..318
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 733..884
FT /note="BMERB"
FT /evidence="ECO:0000259|PROSITE:PS51848"
FT REGION 359..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..492
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 882..911
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 911 AA; 101467 MW; 62DB5F35C20266B2 CRC64;
MAALRKAKRI GKRASKFQYC VTYQSVMIEC TNDKWTPHMI SIAFHRRGRR ILSKILPWLP
SPDNKLRGVA VWPEPEAIEA PITLYKGQKD KSYETKEWEF SVINVDRHGH RKVLASVPIN
VVQYASALPF DQEVKLLLKS VSVKVKKVHL EMSISSVLLK EGKATDDDMI SIASMMSVSN
LSTIGNLEDE DEFTITRFGT GRSISPVTSN DPIPSLEELL EWSQNVTKGY SNVDISNMTT
SWKNGLAFCA IIHHYRPDLI EFYQLTPNSI KENNRLAFTI ASELGIFCPL TPNMMLLTDV
PDKLAVSSFV YQMYNYFTRH VHSAVFKPHL PRQSPSPVSP SLFDISKFEE LSLSISSISP
SSKTTTANPY SKYSHQTTDQ PTPPVSTVTT PPVSTVATPP MSTVTTPPVS TVTTPPVSTV
TTPPVSTVTI PPVSTVTTPP VSTVATPSTS SVATPLDTCS ATSGNDHKEN SVTTLDIHVD
MTEPSTSEES DIVSLESKPH PQEQDRPSRS SLAAIKPMEG KPDKSRRASL PAISPTEDKS
ELYRKQAQAM MKRVGIQKPT TFDALSESTK RKLEKARQKS HGSLTPSNLS PSNLRPSNQP
PSNSSRVLSS CKSDSKLLTV ELAKENEDTE QSGEVGTGEV GTGDVGTGEV ETGEVIVKQK
QERLKLLAPS SKPSRAAKIM SLQPPTNTDT NTDTNTDTNP DTNTDFAEST DSTDVQKPLN
DTDSVSAWKN HERDLNKDIL QSQSDYVKTE LILLQGQLQP LQERSTTIET EIREAMSRGD
DKKEELLTVE YFKVLNEKNS LIKKQIELNL LEKEEDLEKR QFFINRELRP LAAMTDEEKT
KEQKEREEEL IKELVELINE RDWLDQRLTN TTQPISVECT NEKEIESTKR RSSLSKKLSL
ERRDNKECAI S
//
