ID A0A1X7UIZ5_AMPQE Unreviewed; 790 AA.
AC A0A1X7UIZ5;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:Aqu2.1.27453_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.27453_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.27453_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the multicopper oxidase family.
CC {ECO:0000256|ARBA:ARBA00010609}.
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DR AlphaFoldDB; A0A1X7UIZ5; -.
DR EnsemblMetazoa; Aqu2.1.27453_001; Aqu2.1.27453_001; Aqu2.1.27453.
DR eggNOG; KOG1263; Eukaryota.
DR InParanoid; A0A1X7UIZ5; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd13858; CuRO_1_tcLCC2_insect_like; 1.
DR CDD; cd13884; CuRO_2_tcLCC_insect_like; 1.
DR CDD; cd13905; CuRO_3_tcLLC2_insect_like; 1.
DR Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 3.
DR InterPro; IPR011707; Cu-oxidase-like_N.
DR InterPro; IPR001117; Cu-oxidase_2nd.
DR InterPro; IPR011706; Cu-oxidase_C.
DR InterPro; IPR045087; Cu-oxidase_fam.
DR InterPro; IPR033138; Cu_oxidase_CS.
DR InterPro; IPR002355; Cu_oxidase_Cu_BS.
DR InterPro; IPR008972; Cupredoxin.
DR PANTHER; PTHR11709:SF218; FI03373P-RELATED; 1.
DR PANTHER; PTHR11709; MULTI-COPPER OXIDASE; 1.
DR Pfam; PF00394; Cu-oxidase; 1.
DR Pfam; PF07731; Cu-oxidase_2; 1.
DR Pfam; PF07732; Cu-oxidase_3; 1.
DR SUPFAM; SSF49503; Cupredoxins; 3.
DR PROSITE; PS00079; MULTICOPPER_OXIDASE1; 1.
DR PROSITE; PS00080; MULTICOPPER_OXIDASE2; 1.
PE 3: Inferred from homology;
KW Copper {ECO:0000256|ARBA:ARBA00023008}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 729..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 74..185
FT /note="Plastocyanin-like"
FT /evidence="ECO:0000259|Pfam:PF07732"
FT DOMAIN 262..394
FT /note="Plastocyanin-like"
FT /evidence="ECO:0000259|Pfam:PF00394"
FT DOMAIN 563..678
FT /note="Plastocyanin-like"
FT /evidence="ECO:0000259|Pfam:PF07731"
SQ SEQUENCE 790 AA; 89010 MW; DF186610AEFB2208 CRC64;
MASDPDDECE FTLEIDMLQT FTKYEVDTTT DRQENIRGNA GRVWNFDDMG VLQPLGTSGP
CGRDTPDDQC TEAFTVDGET FRSFIAVNGR IPGPTLIVNE SQLVQVNVIN KLASESVSVH
WHGMHQRNSN WMDGVEHVTQ CGIPPGASFT YIFEATPYGT HWYHSHSGAQ RTDGLFGALI
VKEKDENTDL MAKLIKLDID NYEDNPEDHT LTLLDWQRSS SLDLFTQIHS GIRYFEVDVA
SKLNTMQQSD QTYSSDGAEV GPVSYWSGLI NGKGRHKGIK LDTDNFKFEL SVFEVSEGNT
YRFRLIGAQS LFAYCFSIDG HKLRVIATDG EFVDPSEEYD FIIIHSGERY DFLLKKDDTT
DTTRKHFLIR AVTLEVNSDN WLAEENRAEA ILTYDKDDLK NNNNIKTTVM NSKILKDRCD
NKKCMALNCP FENFPSKYKT KCIHIHDLNS LSSLNDLTNM NIKKDLFFNF AFEGPRRTST
INARNLKLPT EPPTLSNNND IPMRCGTEAR HHATCSMATG TVLSPDCYCT YVVDVNSDGQ
TDNKYVRLVL SAIGKKKAVE QDNPNFLFAH PVHLHGHYFH VAEINFGEYY TETDGDKDGK
LKTANKDITC GDEDGPSCPN PMLSSFAVPK KTAPLKDTLL IPAGGYAVVY FKTDNPGWWF
LHCHIEVHQL EGMGVIINEG GNKKIPAPYT MQKCGNFDFS VPQYMLAIEN KLNPTDPPEK
KCDIKCCKWW VIGSVFISPL VVGFLIAVVA LIIYCSYKAY KKKNSPKTEE EGNKKNEVQS
TQTIAKFTYN
//
