ID A0A1X7UL49_AMPQE Unreviewed; 2025 AA.
AC A0A1X7UL49;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=NF-X1-type domain-containing protein {ECO:0000259|SMART:SM00438};
GN Name=100641176 {ECO:0000313|EnsemblMetazoa:Aqu2.1.28229_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.28229_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.28229_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_011404801.1; XM_011406499.2.
DR EnsemblMetazoa; Aqu2.1.28229_001; Aqu2.1.28229_001; Aqu2.1.28229.
DR GeneID; 100641176; -.
DR KEGG; aqu:100641176; -.
DR eggNOG; KOG1807; Eukaryota.
DR InParanoid; A0A1X7UL49; -.
DR OMA; HISTITC; -.
DR OrthoDB; 2971338at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd17936; EEXXEc_NFX1; 1.
DR CDD; cd06008; NF-X1-zinc-finger; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR SMART; SM00438; ZnF_NFX; 8.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1285..1307
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 1309..1322
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 1423..1441
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 1532..1550
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 1587..1604
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 1638..1651
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 1668..1689
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT DOMAIN 1699..1727
FT /note="NF-X1-type"
FT /evidence="ECO:0000259|SMART:SM00438"
FT REGION 1..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2025 AA; 231990 MW; 685B42BA6FCF47E3 CRC64;
MNSSSSDEEI HIPQINLRER AHGASPFVGG FRRGSRGFRP GGWRGRTDRP GGFRSDISDE
SLDPGSSRGR GDRGRRGRGR DRFQRSDRAR GNDYSSGDRH SAADGPNKRG RGGKDGSRGR
GRGGSRSAHV HRMEFSDLVD LAKSPPSEVV NKIQDDLKGF QESLNSCNKV PEKVKERYIA
AIISLLLKIC QSSDEKANMI IAEFLSDRCS EFHVLLKHYV SETLLSQTNT HNMVSQLLLL
FKQLLTRMPL SAWHILPIND FHEVVMTTSV DYNEHFMVTD LKALYTEAKQ RHMEKKKSSE
IHFEWDNSLY RTIPIVPTMD EICSSDPPRL RSNIINGAYT DWEHYYDVQF RLLREDFVAP
LRRGVTLYLS QERTGRLTDI NVYKDVYILK PEFTENGICY KVQFDVSRFR QRKSWAHSKR
LIFGSLLCFS PKNNQFRETV YFATVVERKP EDLVKGYFYV QFENSQEIFQ HIHKTCFVVI
ESRAYFEAIR HILVSLQKAE TGTMPFKRYL IDNNPRPVNR PSYLQNGTYY DITWLYPESK
QKSHLSLEID ITDEHSWPTE DQLELDASQI NAIRMALTQE ISVIQGPPGT GKTYIGYKIV
QTLLQNRDIW DPTHSSPILV MCYTNHALDQ FLQGIIHQKI YLEDNTDEIL LHYPYDMHSK
VERVPDVVRI GGRSKSEEIQ KHSLWNARGN TVPYYKLRNL RELKDDITTE ALKIPLHSNA
NVMYDVVNEY MVGREGMDLL RDVINPSHFY ELSLLGEEFD DIGLSLELWL GFWTLPTETA
HQFSISSSIP PDTEHEYTSA PDDQSACDDD DVMLENEEEN IDIIGEAEIE ESNRQLDDVG
FKRLKLEDKH VSIKEDDILS QHIKQEDKDH SQFKIEKKDS REIKKILQAI RYIDPLEEDE
EIEIADVRNL PMISKYRLFR LWVVKLQRML TDVTQRKLIS LEEKCRAYKE AQMEVDRIAL
EKADVIGMTT TGAAKYQHIL HLVKPKIVIV EEAAEVLESH IVSALNAGTE HLILIGDHKQ
LRPKPNEYEL AKKHHLEISL FERLLLNNLP HATLLIQHRM RPQISSLVCP FIYDELIDHE
TVTTYENIRS CDKNMFFFNH KHPETEIEHL LSHSNVGEAK LVVSLCRHLL KQGYKPSQIT
VLTAYTGQLL CVRDMMPKKN FEGVQVVNID NFQGEENDII LLSLVRNNEL KKVGFLKEEN
RVCVALSRAR MGFYCFGNFD MLRAVVPIWD RILSYIESEG CFGSSFPIHC HNHPQYKISI
EKAEDFIIHF PDGGCNIPCI YRLNCGHHCR RRCHVNDPNH EQYCCKEPCD KLCHRDLHPC
PLRCSDACKR CTYLISQVMP SCGHIQDMEC YKNPAEEQCH NPCSKKCPNG HICHKKCSEY
CGNCIVLVDK IIPRCKHIVQ MYCFLDPSIA ICYEKCQKIY EGCNHKCPKK CFEDCSVSCE
KQIEKVLPCS HIDVIPCSMD PALAKCTKPC QRKRECGHPC KGVCGESCSS YKCSEPVKLT
LPCGHISTIT CHNCSTENVY ECNKPCEKIL SCGHPCKRTC SSPCTTQCTQ RVSFTCCKGH
HTYKVRCFEA KNADLVCDKK CVEKLPCGHA CTNKCGEECS SCAQSVDKHC PCGHKHKFKC
GEYGVCSCKK KCPIILQCGH KCSGDCGECY TKRMHPPCMH QVQVNRFCGH FGSAPCIGLF
DQCQQSCRLS VCPHNKTPCD HKCYEPCHAA QCEEKCIVEC SHSKCTQICS EVCSVPSCTK
PCTKLLDKCH HSCSTVCGEE CISECCPKCS GKKFSEKVKG LGKKANITTE AIIKLNCGHI
YSVNYLNQRF TPKGDQDTLI CPLLCPACSK PFVLPYYWQM TQERAKDIKQ VKRQLPTNPV
TYSPDRHRLA FRKVTLDAET ACALKLFSNA MELKSQLNIT TFIENMLKQT KCKLTMQIVT
DIESELFRLS LLTLAKHVPE TTLSKQPLHS LLQQMDEDHN LRLTYEMYEE YLPAIRSNSV
YEVVPVSLPK ITKGQWYKCR HAGHIYFVPA KYGANCPECT ECHSK
//
