ID A0A1X7UY97_AMPQE Unreviewed; 933 AA.
AC A0A1X7UY97;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0008006|Google:ProtNLM};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.32676_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.32676_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR AlphaFoldDB; A0A1X7UY97; -.
DR EnsemblMetazoa; Aqu2.1.32676_001; Aqu2.1.32676_001; Aqu2.1.32676.
DR InParanoid; A0A1X7UY97; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 9.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR10131:SF94; TNF RECEPTOR-ASSOCIATED FACTOR 6; 1.
DR Pfam; PF13923; zf-C3HC4_2; 2.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR Pfam; PF02176; zf-TRAF; 4.
DR SMART; SM00184; RING; 3.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR SUPFAM; SSF49599; TRAF domain-like; 3.
DR PROSITE; PS00518; ZF_RING_1; 2.
DR PROSITE; PS50089; ZF_RING_2; 2.
DR PROSITE; PS50145; ZF_TRAF; 6.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 23..62
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 103..153
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 166..213
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 336..389
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 399..446
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 573..612
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 653..703
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 716..762
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT ZN_FING 103..153
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 166..213
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 336..389
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 399..446
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 653..703
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 716..762
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
SQ SEQUENCE 933 AA; 107939 MW; 3192ED204F20A686 CRC64;
MSRFSKDELS FVKEVPEHIE IECPVCLNIL TDPHLVTCCG HNFCGSCIER VKAGDGSCPM
CKDKEYQSFI DKKCSRIING LEVYCSNKEK GCEWKGELKN MSTHLNKEKR EGECQYEEVK
CQYKECQERK QRRYLKYHED RECLQRPVLC QYCGEIGTFL FITKDHYEEC WYYPVTCPNK
CASTTMPRFN LEYHIDNKCP LEPVDCVFSW AGCNDKPLRK DVHEHTADTK HMTLLAVAWP
FHCLNIMSCF SKEELVFVKE LPDHVQLECP ICLYILTDPH LVSCCGYNFC GSCIERKKYQ
FMVNKERIRI INGLEVYCSN VKKGCQWKGE LKNMSTHLNK EKREGECQYE KVKCQYEECQ
ERMQRRYLKR HKDKECPQRP FECEHCGEEG TFLSITKNHY KECCWYPVTC PRGCASTTMP
RFNLKHHIDN QCPLEPVDCA FSWAGCNDKP LRKDVHVHTA DTKHMTLLAV ACGQLKKENE
QIKEDNEKIK FEVKTKAKFK FHIHTAIANG LSIPLLPIDV TLNLRTPSLR AVYFYSNVCG
QYMSLLPLLN MSQFSKEELS FVKEVPEQIE IECPVCLDIL TDPHLVTCCG HNFCGSCIER
VKAGDGPCPM CKEKKYQSFI DKKCSRIING LEVYCNNKKK GCQWKGELKN MSTHLNKEKR
EGECEYEEVK CRYEKCQERK QRKHIKLHED HRCPQRIVEC KYCGGKGTFL FITKDHYEEC
RQYPVTCPNK CLSTNMPRYK LKYHISKCPL EQVDCVFSWA GCNDKPLRKD IDEHTADTKH
MTLLAAACGQ LKKDVEILKY ENATLKYHIH SAVADNSYPS LPIDITAESG VVHFYSGPCG
RHMSARIIEG GLFAETFMLI AFHEGIFDAN FQPKLSKIFA KNNNTDAPLI TDTEATYKQL
PNDVLGTITN CNNLPPGVIK KNIDHLSYTI YAI
//
