ID A0A1X7V3F7_AMPQE Unreviewed; 291 AA.
AC A0A1X7V3F7;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13847};
GN Name=100632071 {ECO:0000313|EnsemblMetazoa:Aqu2.1.34790_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.34790_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.34790_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_003385757.1; XM_003385709.3.
DR AlphaFoldDB; A0A1X7V3F7; -.
DR STRING; 400682.A0A1X7V3F7; -.
DR EnsemblMetazoa; Aqu2.1.34790_001; Aqu2.1.34790_001; Aqu2.1.34790.
DR GeneID; 100632071; -.
DR KEGG; aqu:100632071; -.
DR eggNOG; ENOG502QSAN; Eukaryota.
DR InParanoid; A0A1X7V3F7; -.
DR OMA; SWWEDAT; -.
DR OrthoDB; 45666at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR027625; OvoA_Cterm.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04345; ovoA_Cterm; 1.
DR PANTHER; PTHR45445; -; 1.
DR PANTHER; PTHR45445:SF2; METHYLTRANSFERASE; 1.
DR Pfam; PF13847; Methyltransf_31; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..222
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13847"
SQ SEQUENCE 291 AA; 32770 MW; 9AB3B74C232A03DD CRC64;
MKADLRSAAI VCGALAGVIG SGAVLWRLWK LRIGCRGNEN PYETCKLVDE YMALHYAAPS
EYFTYTFGPK EAVDFPLRCA QLCKRHKSTA VISRALDVGC AVGRSTFELA TDFDEVIGID
FSQAFIDKAR DMVRDGSAPY HMTVEGDLTS DMEARVSSNI ERNRVRFNVG DACSLPDDLG
QFGLVLAANL ICRLPRPLDF LNKLKDLVVP AGILVITSPY TWLEQYTPKS YWIAGFMQNG
ERKRGFDALK DILSPDFILL EEDNMPFLIR ETCRKHQWTV AHATVWMRRI Q
//
