ID A0A1X7V4V9_AMPQE Unreviewed; 965 AA.
AC A0A1X7V4V9;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN Name=109581195 {ECO:0000313|EnsemblMetazoa:Aqu2.1.35028_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.35028_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.35028_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019850627.1; XM_019995068.1.
DR AlphaFoldDB; A0A1X7V4V9; -.
DR STRING; 400682.A0A1X7V4V9; -.
DR EnsemblMetazoa; Aqu2.1.35028_001; Aqu2.1.35028_001; Aqu2.1.35028.
DR GeneID; 109581195; -.
DR eggNOG; KOG4441; Eukaryota.
DR InParanoid; A0A1X7V4V9; -.
DR OrthoDB; 3848080at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF13854; Kelch_5; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00612; Kelch; 2.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 547..634
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT COILED 470..497
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 965 AA; 108211 MW; AB1A020FA0AF2833 CRC64;
MTDTTDADRS TNVYKNAFQK YMLQIDEALG LYPVTMSQLL YSFGCISDKT LNEIEGSGKS
TEGRKTVLMK ALTYAIKIKG EKLNLLADAF LQFEETSPLA NQLRVTDSAE IEEVENPSPD
WSTKVCPKEK ASCILRYHYA KLAVLLDDTK VIANILCGGR VISQNDSTDI KHQSLVEDSR
GILLKAVRKA VSSNHLHLKT FIDALKTAEY DAISKDLLKD YQEHIEQDSF ARSRRESNRT
VSKEIIAANE NFAGIRAIFE KDFDLICKII KKHRFTLEDL KKFVKAYSDG YIPDISKQDT
KGVLEFVCDK CTLIDINYLE AVVQEFDVAS AIIHIQSFTT NIKELCRYVT VRNVLDEKFF
LSRSTQLLKN DLAIEMIIDQ NPDHITLQFI KDAISTSFGS LAKSVQLVNI KEIDDMLLVT
CLFPKYLSAS VLVPESAMEL MQRRGLVELT IDGSIYWKKE KDHIITKRTI PNDQHQLEEV
VKELEESQKE SRRLSMEVKI LREGLMHDSN NGIEMQETVI GNDDETVEMK DAATQANILE
INRKKIIVEL LKESLDQTLG FNIEEGQGAM YDDKEQSVFI TKITPGGLAE KDGRLKAGDC
IVSVNGVYIN TKAKALDSLT ATTNLYAIIA IRESISENTN TQYSQYSPSV NKKVKRRSMI
YRPSVPGCVV NFEKCASLPV AITNAQAVLY RNKVMVGGQD VPTGADYILE YDIRADNWQV
FIKSPVHLFA LTVFQNQLLV VGGFDFNQQK YSARVYSLYI DERNHFLRDD IIPPMLTARA
QASVASQDQN IAVAGGRDAK SNLRSIEVFH APTAQWHTAH SLLSERSSVR SILHKGSWYL
LGGDMDPSVR SKNVRLKFKM LASSAVQKYG SISYMKTIQK PGNGEGAHSA VVTINDMIVV
IGAGGTRKIY SLCREEGPIS WIELGELPIV LTDSCAVTLE DQVLLIGGKD ENGKITDSVY
FMNLY
//
