ID A0A1X7V5X8_AMPQE Unreviewed; 215 AA.
AC A0A1X7V5X8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=PCNA-associated factor {ECO:0000256|ARBA:ARBA00013777};
DE AltName: Full=PCNA-associated factor of 15 kDa {ECO:0000256|ARBA:ARBA00030014};
DE AltName: Full=PCNA-clamp-associated factor {ECO:0000256|ARBA:ARBA00031186};
GN Name=105312286 {ECO:0000313|EnsemblMetazoa:Aqu2.1.35219_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.35219_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.35219_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC {ECO:0000256|ARBA:ARBA00004556}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_011403116.1; XM_011404814.2.
DR AlphaFoldDB; A0A1X7V5X8; -.
DR STRING; 400682.A0A1X7V5X8; -.
DR EnsemblMetazoa; Aqu2.1.35219_001; Aqu2.1.35219_001; Aqu2.1.35219.
DR GeneID; 105312286; -.
DR KEGG; aqu:105312286; -.
DR InParanoid; A0A1X7V5X8; -.
DR OrthoDB; 3269561at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR InterPro; IPR040444; PCNA-AF.
DR InterPro; IPR031444; PCNA-AF_dom.
DR PANTHER; PTHR15679; PCNA-ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR15679:SF8; PCNA-ASSOCIATED FACTOR; 1.
DR Pfam; PF15715; PAF; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 1..138
FT /note="PCNA-associated factor histone-like"
FT /evidence="ECO:0000259|Pfam:PF15715"
FT REGION 1..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..191
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 215 AA; 23636 MW; E5227648180929EF CRC64;
MVRTKANNAC TRKAVAAKAP RKSLGGGGGG VRHNFTSPSS AGRKKGKGVG GNPIRVHPTP
AWQKGIDLFM GGGSSKETAA SSSSSRSEEN KENFPKGKGK RGVSGKERHK GEKDTAAAVI
DVEEMNNDED DREQDEETEE INEQSEEERE DEELEELKSE DEEEEVEEEE EIEEDDILEE
EEEEEEEEEG GNKSMLDSLP TDLFTTQDSD NDNDS
//
