ID A0A1X7VDC4_AMPQE Unreviewed; 1476 AA.
AC A0A1X7VDC4;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:Aqu2.1.37517_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.37517_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.37517_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR EnsemblMetazoa; Aqu2.1.37517_001; Aqu2.1.37517_001; Aqu2.1.37517.
DR eggNOG; KOG4177; Eukaryota.
DR InParanoid; A0A1X7VDC4; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24198; ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24198:SF165; IPT_TIG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF13637; Ank_4; 2.
DR SMART; SM00248; ANK; 19.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 11.
DR PROSITE; PS50088; ANK_REPEAT; 13.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 60..80
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 94..127
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 128..148
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 162..195
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 196..216
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 264..284
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 298..331
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 332..356
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 366..399
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 400..420
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 468..491
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 536..559
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 604..624
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 794..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1344..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1440..1476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..810
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1390..1406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1476 AA; 165043 MW; F08B851BB019447F CRC64;
MACIYNHLPV VEYLTGQPNC NINSNNERHP LLAAADKEHL EIVKHLIEST DCGINAKGRD
GLTPLHVACL NRNFETVQFL TSSSECNIEA EDNDQDRPLH LACRSGNLDI VRHLVIDKHC
DVNAKGRNGY TPLHMACLNR NFETVQFLTS STECNIEAED NDQDRPLHLA CRSGNLDIVR
HLVIDKHCDV NAKGWDGLTP LHVACLNRNF ETVQFLTSSS ECNIEAEDND QDRPLHLACG
SGNLDIVRHL VIDKHCDVNA KGWDGLTPLH VACLNRNFET VQFLTSSSEC NIEAEDNDQD
RPLHLACGSG NLDIVRHLVI DKHCDVNAKG RDGYTPLHYA CEKGHFEMAK ILTDHSQCNT
EAESNSNDRP LHKACESGNL DIVPHLVIDK HCNVNAKGRN GYTPLHAACL NGNFETVQFL
TSSTECNIEA EDNDQDRPLH LACRLGNVDI VRHLVIDKHC YVNAKGWHDY TALHYACGKG
HFEIVKILTN HPQCNIEAED ILNDRPIHKV YESGNVDIVR HLVVDKHCDV NAKRGNGYTP
LHYACEKGHF EIVKILTNHP QCNLEAKDIL NDRPLHKAYE SGNVDIVRHL VVDKHCDVNA
KRRNGYAPLH YACEEGHFEI VKILTNDPQC NIEAKSYCNR RPLDLAFRHK PPTKSHIDIV
DYLIDVKGCD TQGIDRKATN FLHIRQSSGI ALLRVVKCIL TGPPGAGKST LKKRLLNQSL
DTGPSLSTGV IDAAVQVNSF RKLSQHNAVV TTEWKEQELD EEAILITKKL LPANNTSDES
TRPTQSTLFI ENTRTSSFEK KSRSPEEIGL SDQHDNVPSV TSSPTFMHSQ VIDTTSYNEK
SSDMEHENIA DSCGAPVNCE EEETKTDTEV QNSSSSVIKG FSDFLSKIPV RKREEYERKF
EEEKDDNHTM LHIIDTGGQP EFHEILPALI TGPAINLLVF KLTENLRSRY EIIYRTSAGD
SKPYETSLTH EELGSAAVER EFRKNGRFSE SQLDKISLRE KGDPLNTKRL VALLKHLYIV
AGPMKDKAGQ KTVNYYFMPC ALKPADVERE ERDGSVSPAP LLICFECGYT PVGVFCCLVV
YLLDQKTDQV LEWKLTGNDQ YRNRITFQVG QYYDTVTLIS RATYLEIWVQ QQMSPSLNDL
SDKILSSLHK GLDTVTQSLH YTYKSKHMFG VPCTCTGVPH PAVIEHCSEG AKCTNGNLLK
LGEKHLYWSK KVVDLNTGAQ KSNKSQPSGN VATENEILPE SIFQSHLADI TNAISSDVTR
VAVDLCTKFL LPTSLKNDLS SLLGVSDFDK ANKITSYIHK HIISNSTVEA AEYLTTVCNV
LYQRDDMRLR KIIADICKEL GKPIPKGNKK TKSKSYASKR VHGTAGGRQP KDMQGEMSVN
KRLKLSELSV IDDESQSSNN TSSVLGVKRH SEDESSESVL TNKKQKFIQS SSNEVISLLS
DDDDVLILDP PSPLDKGYGK RSTGNKPHRR KTGSKK
//
