ID A0A1X7VG44_AMPQE Unreviewed; 453 AA.
AC A0A1X7VG44;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=PCI domain-containing protein {ECO:0000259|PROSITE:PS50250};
GN Name=100636108 {ECO:0000313|EnsemblMetazoa:Aqu2.1.38467_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.38467_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.38467_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the proteasome subunit p55 family.
CC {ECO:0000256|ARBA:ARBA00006397}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_019849217.1; XM_019993658.1.
DR AlphaFoldDB; A0A1X7VG44; -.
DR STRING; 400682.A0A1X7VG44; -.
DR EnsemblMetazoa; Aqu2.1.38467_001; Aqu2.1.38467_001; Aqu2.1.38467.
DR GeneID; 100636108; -.
DR KEGG; aqu:100636108; -.
DR eggNOG; KOG1498; Eukaryota.
DR InParanoid; A0A1X7VG44; -.
DR OrthoDB; 158659at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR040134; PSMD12/CSN4.
DR InterPro; IPR040896; RPN5_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10855:SF1; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12; 1.
DR PANTHER; PTHR10855; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF18098; RPN5_C; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 234..416
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 453 AA; 52284 MW; 98CD17EE700DB993 CRC64;
MSEGRLVKME VDYSATVDEV LPECQELAKA GEVKKAFEKL LSVEKKTRMS GDALSTGRVL
KTIVQLCFDL RDWDSLNEHI VLLSKRRAQL KTAVAAMVEE ACKLVDQTPD KDTKLKLIST
LRTVTEGKIY VEVPRARLTM ELAKMTESDG DISKAADILQ ELQVETYGSM EREEKVLFVI
EQMRLCLAKK DYIRAQIISK KVSTKFFLGD TETIQDLKLR YYHLMIQMCQ HSKSYLDICR
HYRSIFDTPK VQAEEQAWKE ALKNSVLYVL LAPHNNEQSD LLHRIYEEKK LSMIPLYKTL
MECFRRQELL NWSMFQASYT AVLREGLPEE PATGVFAVGT EEGDMHWKDF EKKLIEHNLC
VLAKYYTRIS LSRLSQLLLL NEQESEVYIS DLVTKKTIYA RIDRPAGVVS FSQTQDPSEI
LNEWSTNLSN LMTLVSKTTH LINKEEMVHR LVK
//
