ID A0A1X7VIT7_AMPQE Unreviewed; 1007 AA.
AC A0A1X7VIT7;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Peptidase M16C associated domain-containing protein {ECO:0000259|SMART:SM01264};
GN Name=100640355 {ECO:0000313|EnsemblMetazoa:Aqu2.1.39957_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.39957_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.39957_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|RuleBase:RU004447}.
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DR RefSeq; XP_019848664.1; XM_019993105.1.
DR AlphaFoldDB; A0A1X7VIT7; -.
DR STRING; 400682.A0A1X7VIT7; -.
DR EnsemblMetazoa; Aqu2.1.39957_001; Aqu2.1.39957_001; Aqu2.1.39957.
DR GeneID; 100640355; -.
DR eggNOG; KOG2019; Eukaryota.
DR InParanoid; A0A1X7VIT7; -.
DR OrthoDB; 5477696at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR InterPro; IPR013578; Peptidase_M16C_assoc.
DR PANTHER; PTHR43016; PRESEQUENCE PROTEASE; 1.
DR PANTHER; PTHR43016:SF13; PRESEQUENCE PROTEASE, MITOCHONDRIAL; 1.
DR Pfam; PF08367; M16C_assoc; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 2.
DR SMART; SM01264; M16C_associated; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 503..751
FT /note="Peptidase M16C associated"
FT /evidence="ECO:0000259|SMART:SM01264"
SQ SEQUENCE 1007 AA; 113536 MW; A32A285DD8027CD3 CRC64;
MAAQLFSAPR LLSRRRRLIH LNNTVFNSTR REDVSKLSVA INDRISGYRV TGVTEVSDFN
LKAIELLHES TKAQHLHLVR QDSNNVFGVG FRTTPMDSTG ISHILEHTTL CGSAHYPVRD
PFFKMLTRSL ATFMNAFTAN DWTFYPFSTQ NYNDYRNLLS VYCDCVFHPN LKKMDFHQEG
WRLEHEDPND RNTPLVFKGV VFNEMKGMFS NAEYLFDTEL QRKLLPSHTY SHVSGGAPLN
ILDLTWDSLK EFHAKHYHPS NSYFYTYGDI PLSDHLSFID ENVLSKFSVS TPAAAIPLEA
RWNQPRSHEI YCAPDPMAPD PNKQTTVGVA YLLGPITDSY EGLLLSILTK LLIDGAASPF
YQSLIDSNIG SDYSPSTGYN DGTKDSYFSV GLQGISTEDA EKVKQIITET FHKVYQEGFP
EERVKAILHQ VEIGLKHQSS NFGLALLMHF ITPWIHGASP TSLLQINQNV ENFKDHMAND
PNYLKEKIKE YFIDNKHNLT LVMSPDVEYN KKQKELEEEK LRLLVSSLSE DDKQRVYDEG
LQLQEDQNKH QTSDCLPSLS VADVDKTTPI TELIHEDHGS IPIQYCVQPT NGISYLQFLS
SCRDLPDDLK PYLPLFCSVI TKMGTQDLDY RQLSQQIDLY TGGSVCVGTH VASHHSIPNQ
FEQAIALTSH CLDRHLPYML SIWEDIFNKP QLQDEQRLQT LIAMEASSLA VNVSRSGHRY
AMTASASSLS PAAMMAEKYG GISQVKFMKD IAETSDLKPV LEKLASIAVA VLDTGCMRVA
FNVTEPQFTV ASEAAEGFLD NLPGSITDTP LFMEEGTVTP TLSHTHYQLP FQVYYVGQSY
RTVPYTHEDS PSLRVLAQLM GWKYLHKEIR EKGGAYGGGA KHGNGIFSFF SYRDPHSLDT
VNRFNDSIDW VTSRSFTDED VEEAKLSVFS QVDSPVSPGS KGSSLFLQGL THEMRAQYRS
RLFEVSGDHL VSVATKYLKE AEHKGSVIIG PEIKTLSPEW TIKHFSL
//
