ID A0A1X7VNR1_AMPQE Unreviewed; 1666 AA.
AC A0A1X7VNR1;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=C3H1-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=109593049 {ECO:0000313|EnsemblMetazoa:Aqu2.1.41023_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.41023_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.41023_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019863870.1; XM_020008311.1.
DR STRING; 400682.A0A1X7VNR1; -.
DR EnsemblMetazoa; Aqu2.1.41023_001; Aqu2.1.41023_001; Aqu2.1.41023.
DR GeneID; 109593049; -.
DR KEGG; aqu:109593049; -.
DR InParanoid; A0A1X7VNR1; -.
DR OrthoDB; 5479694at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.30.1190; -; 1.
DR Gene3D; 3.90.1140.10; Cyclic phosphodiesterase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR019510; AKAP7-like_phosphoesterase.
DR InterPro; IPR009097; Cyclic_Pdiesterase.
DR InterPro; IPR042653; Leng9.
DR InterPro; IPR040459; MJ1316.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR46729; LEUKOCYTE RECEPTOR CLUSTER MEMBER 9; 1.
DR PANTHER; PTHR46729:SF1; LEUKOCYTE RECEPTOR CLUSTER MEMBER 9; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF10469; AKAP7_NLS; 1.
DR Pfam; PF04457; MJ1316; 1.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF05773; RWD; 1.
DR SMART; SM00393; R3H; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF55144; LigT-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF82708; R3H domain; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51061; R3H; 1.
DR PROSITE; PS50908; RWD; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 9..100
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
FT DOMAIN 124..151
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 1604..1666
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT ZN_FING 124..151
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 149..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1666 AA; 186446 MW; E44447FC912C388E CRC64;
MAAESGLTEE LETLRSIYTS EELAVIQEGE TTVIYNYNSS IKLTIKLNAP YPASLPSITA
PSHLSSLGLI SHLESVATPL LGTPMLYAII DAAKDWLDGH ALSLAPPTGG GKERGDKSPS
PIAASSQTTC KFYLQGKCRF GDKCKNYHPG AKTQTDTHTK QTDTHTSAST RTQTKTKGTK
TEASNGGGGG SSSKKTDERD DEDGFNSKKD KMRTATEVIS RILWDPDLPS EEFSVGYLDR
FIGILEKPFK EFSWEDISTV GANVLAVPKH RIQYFKYKDL IVWDKRNQTD NFFGSRGGQT
IQEIVTKNQQ ATASPQASSD DQESLSLLEA ETEYEPESTE KTSRYYSDVT RPTHFVCLHI
NDQEVVDEVK KVVSHVTGLN PQLKEGLINI RALHVTLCMV RLTSDEQIEK AKTVLQSARL
QFISLLPSCT QLAFTGVDNF RERLIYVKMK EEPSLSKFVS HLIEQFQLAG LKTPGNHEEY
TPHITIVKLS RPMQRELKTD IINPACYQPY LSHSLGQQPV SSVYLCSMHA PAQEDGFYLR
YSTLSNSLLG LPESFVSLVQ NQFGLLADLG YLSETDRDAL LSDLRSTVQD QNEERFDEII
EELMRLNKEA MSFESLFTLQ PCVVILRGLP GSGKSFLASH CQEVLKNTTK TVILSADDYF
TGRRGEEERE YVFNPATAYK AHQHVLHQFL SSLANGVKLV IIDNTNTQLW EYRIYTHICD
VLGYPYHILE IPFLSSSNLA ELYRSRNVHG IQPPAIVKMS QRWEEDERRI LVPPKLVYPR
SSSSSSLEPP SYSLLSLCGT QSSSLTDLAN SDCKIVPVYT GLFLSVESQW ELLKTYRPAH
SDLFGSHVTL HFKPTARQLG ELPLGKRVQV QVLGESDNGR VQAVVVELPS HVTSENKSPH
ITISTVPGLP PKLANAMLQS KLIKQNKLIY LEGVLGLVVR QATREEREGK ELMDESLSSL
SFHTITSQTE LKSIAPKLLY TDNDEASPVA TSIPYKENAG ILTGEQEITQ LFIFDFDGTL
FIPPGNYEGR REYERLTGKK WHRKGWLTHA DSLLPPLHVQ PGPALSDYRS HDNRAGSYTV
ILTGRTDSVR LGLVYVLEKS QLYPQRIICK PNETSETTSA YKMRVVKELL EELPNVNLVK
FWDDIAENLS AIQRLATQKG KGFGRPVQFE IIDATKMSDI HGDIRSPKKR LPNPVTQFGS
YLQGYLTLHG LLPSLDHKAG IQEGLLFIST QFAKLVHYNG DPLNLSYEFG SSPLNRIGDV
DVCLLAPPGH THIEWLQLLA KELEACGMKY VHVGHSSRCP RLKILLQFSH TPNIEFDIVI
AIVHKEEFFS RGGEGKMSAS KVGETREAGD SVSKIAISGA LFMERIESMV KRTGVSLETI
GGMVEMTLQL LMAKREKGNA YHCIRSFHIV KLLIDYIDSH SQLPSLNHDE LFKSFIYHVS
QMTFDNWKNL LTEFVPEEYI PRLMSIFKEA STILSVETIS LPVYEDILKR SVFPPDGYTP
VEIRLSGTDS LKKWKSRMLI EARLPSYIRQ LLSRGLDVVS NGNKNNDRFC FAVPQSDSSK
GILQQVLRPF WNEMADIKKE DGVSIHLTLG LPTDAQSHVN AATDSRARGV LESVRLFVSS
EQRELHLPSS LTAHTRLLVH ETAETLGLAH SSVGKGNNRH IVLKKL
//
