ID A0A1X7VQ79_AMPQE Unreviewed; 931 AA.
AC A0A1X7VQ79;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Calx-beta domain-containing protein {ECO:0000259|SMART:SM00237};
GN Name=109587784 {ECO:0000313|EnsemblMetazoa:Aqu2.1.42029_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.42029_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.42029_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019859564.1; XM_020004005.1.
DR AlphaFoldDB; A0A1X7VQ79; -.
DR EnsemblMetazoa; Aqu2.1.42029_001; Aqu2.1.42029_001; Aqu2.1.42029.
DR GeneID; 109587784; -.
DR KEGG; aqu:109587784; -.
DR eggNOG; KOG1216; Eukaryota.
DR InParanoid; A0A1X7VQ79; -.
DR OrthoDB; 2957087at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 2.60.40.2030; -; 1.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR035234; IgGFc-bd_N.
DR PANTHER; PTHR46534; IGGFC_BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46534:SF1; IGGFC_BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03160; Calx-beta; 1.
DR Pfam; PF17517; IgGFc_binding; 1.
DR SMART; SM00237; Calx_beta; 1.
DR SUPFAM; SSF141072; CalX-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..931
FT /note="Calx-beta domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010866600"
FT TRANSMEM 851..878
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 464..562
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT REGION 816..838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 931 AA; 100243 MW; 7BFB477AAE42F733 CRC64;
MKLLFITLSF LFFAFAADAQ SASNLSSYGS EFFVGFYEHV HTGITHIFYI HTKLTTSVSF
SISSLDGVFS YTGTTTSQNP AAVTIPASYE VRAETSTYRD KGLRVTSLET EPISVLAWSY
RSAADYMSYL ALPCHAQPTT EYTYYVVSTY GWSSQKSQFL IIGCKFNTTI TIIPNNRISV
PADPQVSSSP IVSIFPGNTY KFTLNSLQTF FVSESYVDLT GTMIVSNKPI TVISGHEAAQ
VPTHTLDADP IVTQLTPTIT WGKRFLLAPH YSRQNGQSYK ILALNNMTSA VQTCATSSGN
YNATNITFNA NNTAWVYTLQ GTYCSIIAND SIYVAQIGVS SNYAQTSSGD PALYTIPPIE
QYEQEAQFTS FTQATGYYSV VVPNDSYFTN SLRINGFVQN ITFIPIYSSN GTVLGYGYSA
STSGSNIISH TNSQGRLFVS VYGFTTYGGY GYPGSMMLNP INGDAVTSVP EVTFSDTEFT
VNEGDGMAYV YLETNDAGLQ ANITVRLFSN PTTVDTALIG QDYSSFSILV TFSGNETTKS
VSIPIIDDDY AEPTQYFTIS IESPNKNDDI TFPITEAVVK IIDNDAIAIG FLDSQFSIGG
NGGLTYINVG IVSGSLEPDG SSTFTLEIII VEGQNSSFIS GSLSSFNPVI SYGFNLSQLS
TYNPNSTNQS LSALLSVSAA SINVTLEMAN AEIVPVVPIF PSSAQAFMSS SVFSSMMGMY
SSSMIVCYTT GMGESSSTMI APTSSSSMAS SSSTTTNVPV SISIITVSES AIMTTVHDTV
IQTATVCPSL GNTPLLSIST TTYTTTATVT ASASACRSSN SSTPTRSSSD KSQPTPETNA
FTEKIEVVGS ALYFGIAVII IAVLVLIALS IFCCVFCYKR GHQKGRISEI KFDREIEMSG
TNPLYDDPSD TMSYRSSVPS VDEKKLLQFM Q
//
