GenomeNet

Database: UniProt
Entry: A0A1X7VSW4_AMPQE
LinkDB: A0A1X7VSW4_AMPQE
Original site: A0A1X7VSW4_AMPQE 
ID   A0A1X7VSW4_AMPQE        Unreviewed;      2721 AA.
AC   A0A1X7VSW4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   28-FEB-2018, entry version 8.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:Aqu2.1.42503_001};
OS   Amphimedon queenslandica (Sponge).
OC   Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC   Haplosclerida; Niphatidae; Amphimedon.
OX   NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.42503_001, ECO:0000313|Proteomes:UP000007879};
RN   [1] {ECO:0000313|EnsemblMetazoa:Aqu2.1.42503_001, ECO:0000313|Proteomes:UP000007879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E.,
RA   Glavina del Rio T., Bruce D., Barry K., Pitluck S., Srivastava M.,
RA   Simakov O., Chapman J., Mitros T., Hellsten U., Putnam N.H., Fahey B.,
RA   Gauthier M., Larroux C., Richards G.S., Stanke M., Adamska M.,
RA   Darling A., Dacre M., Degnan S.M., Zhai Y., Adamski M., Calcino A.,
RA   Cummins S.F., Goodstein D.M., Harris C., Shu S., Woodcroft B.,
RA   Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT   "The genome of the haplosclerid demosponge Amphimedon queenslandica
RT   and the evolution of animal complexity.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:Aqu2.1.42503_001}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2017) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EnsemblMetazoa; Aqu2.1.42503_001; Aqu2.1.42503_001; Aqu2.1.42503.
DR   Proteomes; UP000007879; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007879};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007879};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2252   2271       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2283   2301       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2313   2330       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2335   2354       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2374   2401       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2421   2446       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2531   2551       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      118    173       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      180    230       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      238    297       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      304    355       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      378    434       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2664   2684       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2721 AA;  311299 MW;  00E0B284589A7B24 CRC64;
     MALRVESDHQ ATSSFLHIGD TISLYAEGDV SGFISTLGLV DDRVVVRPTS GTPLNPPMKF
     RDCLFKIYPM QRYGAQEQFK KATQSTKSMP DVVILQKLQT AADQEREQSR IESEKQWGQP
     VKYGTTMIQL RHVKSNKFLT VTKRSSAQVE KKAMKVSLDF QGSENAWFYI TPLYKLRTSG
     DNVIIGDKVV LTAITANQAL HVSELSLPDH DDCKEVNAIA DHTSWKIQLF MDYKEDKEDI
     LRGGDVVRLF HAEQEKFLTC DKLDKLKGQL QVFLRFSARA TKTDATSSKA LWEVEVVHHD
     PCRGGAGHWN YLYRFKHLAT DTYLAAREDP DTTADPTRAK LRGSDTDDVY YLCTDQDVPE
     EPIFTIFELD STTIQPHDGQ VPRSSYVRLR HARTLTWVHA TNILIDRESK SPVMFKLGLA
     TLREDKEAFA IVHVSPQEVR DLDFANDAAK ALSSAADIME GGHHLQPTQR KNVIKLLEDL
     VYFTVRKENS GETQKALHVQ GKPDRDRQKL IREQNVLKAI FRLLSVPLPI NKEGSRLLFE
     MADLSEQKHE SLRYMYQLCY RVIEQTQNNY RKNQEHIAET FFQVMQSQIG YNIRAEDTLA
     ALVNDNVKLL ETHIRETEIE TFVNLLKKSQ DPKFLTYLGD LCVSKGTAIQ KVQGMVCEVV
     LKPEHSDILM KLVSVDRESK KMVLHYSNDD ELCERPLELI ADSAAHGNPS DSKVLEYFRA
     QLDLFAQMCF NRQYLGINEV KRQLPIRLVL NCMENCNLTY SLRAAFCRIM YCVYLDTSPQ
     EVVNPVGYSR LWDHIPTDVV LHDYCPWKEN MADKSESVSD DDETTAEVDK SDVSRRRSMF
     QQQHKEESIL RGTTNFVESY LHERSVWKLD DKEQNVLTYE VVCLARMMVY FGFYDFSKLL
     SLTYVLLDGL DNREATPIHH SHFLTTSGLT SSRGVLGSLV GSSAAHFFPR SESLDGNDSH
     KSDYERSDPA VINTKRKILE IIDFIMDVRL DLRITNLLVI YKKEFSLLSD GNSNQSPDPS
     DLDSVDILKQ FEVIFRGNQD LKMDLDDSQG KQLLRVLLQM SMSKNPHLSL QALKLITRHF
     SQRSELTKCF TQVQLLVSQK EKSNYQRIRT NLEKLKTLVD EAELWITKTE DLVVGKKKKH
     ERRLSKGGPQ AELEATVAAA LDYVSSSKDT KMSIKKQPRV QSEGSDGNQG SVKSLSPKYD
     QVLKILSSLT DICNGDDRSF EQRLLKNMGA LQVILDLLQV PYNKAYDTKM SEIMHQGHKF
     LQNFCRGNEA NQLLLHRNLK LFINSGHPTV EVVTLTEVFK DNAALCQEVQ ESEIQYFLHC
     IEKGRDIRYL QFLQTIMKVH GQPVKRSQDL VMAEIANAGD DVLLFFHDQP FEVFIDLMKK
     EQGTALPTSN LIYHLNLLRL LTICTEGKNV NTEMRCHSLL PLDDIVKVIT HPKCIPEVKR
     EYLDFLLHCY IDAEVDNKET FTKDYMWDLF ANMAKDIDAV YKENCTGEEQ YTNYVTCHIP
     VTLTSYFSSP LATHGVKIHQ DVYINLLTSL VRLLQCPFIQ DPQNEEIRQS FEKCCKKMIS
     VARDEGLLLP SNIEDEVQAS AVSQHARRKA LQWLHKHKEK KQLSEWTLDV SGIQTEEKNK
     HIIGGVQNVV AELNETWDCL IEAEESVLVN ILYNPEALFQ RGTNAFKQAS KKFLSRIVSH
     MEHKVFSEDE LFISSMMHYF TKMMTEDIEL SESGMELRSH LLKVYFTNYL LDKQHFTKQR
     HKSERKQSVV MLAKLATISE DPFSSMQDDM LLVSLGDKSV TLEVVQNQLN KCHVTKLVVN
     IIKSSPSHFV MLSAVNLAVA LLNNGNTIVQ GTMWDLLCTC DSELFFNEIY RRFQMAQNEM
     KNSPTGLIIT ETDGATNLVV VQDRKSTGGT VTSLDIQDQL TLVAANTEGL SRRSTPKRES
     RSDTGPGPSV NVMAGHNVMS TPELKLMKPL LRLLQLFCEN HNSEMQNYLR HQTNSKNSKN
     LILETLQFLD CICGITTGGL VLLSLYIHCE NVEVIDQCLT TLTEYCQGPC HDNQKCISSN
     ESSGIDIVVA LIQTELTALE NYQDLAIQLK KTASQTLLAV MESHHDSDII ERIVLKIGSP
     ETLVNICRTL HKSGSSDDNE NSPVEVGHNI YILAHQLATS NRALQLELDK AVKDPNDAVS
     FYAANTAQIE IVRADRSLER IVFPKHEICK FLTTESQNHV RHVTKCDTQG SKVEDFFNHM
     DSLYEEMLCQ QALRDHSIQY WMSKNIVNWS SLSFYLAVVI NFIVILFYPF GKGNKYIEKT
     SNWSVLFMYL IFSALSGLFW YFARNSRYEK RAWFSIGSLA IVSTLFTIGV KPTLFFMGFF
     QVVIKCVYLA SALGNRGVFT NQLSSFKLLL KDHLIVYHSF NLVLCLLGWI WHEFFYSLLL
     FEIVYREEML QSVMRSLTRN FLSIILTTTL ALILVYLYAI LGYMLLSEDF LMETHPIALV
     SNLTDGFCDS DHCNSKEGGW NVQLEPSCDT LMMCLLTLVR DGVRSGGGIG DVIRKPSSIE
     PLYLLRLIYD LSFFFLVIVI IIQNLIFGVI IDTFATLRAE KNATDNMLKN TCFICGLDRT
     RFENQHITFK EHCEQEHNMW NYLYFVVHLR MKEKTELTGP ESYVYDQIKG HIENRSASAN
     LEWFPRLKCM SLNIEEPEQE QNEMKELQKQ LLEATSLVKV LSHQLTDLRD KMNEQRKVIQ
     RKQLHATLPS SLHRFASMSH N
//
DBGET integrated database retrieval system