ID A0A1X8WL51_LEPIR Unreviewed; 305 AA.
AC A0A1X8WL51;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:OCC28462.1};
GN ORFNames=GNX_2989 {ECO:0000313|EMBL:OCC28462.1};
OS Leptospira interrogans serovar Canicola.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=211880 {ECO:0000313|EMBL:OCC28462.1, ECO:0000313|Proteomes:UP000093180};
RN [1] {ECO:0000313|EMBL:OCC28462.1, ECO:0000313|Proteomes:UP000093180}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tande {ECO:0000313|EMBL:OCC28462.1,
RC ECO:0000313|Proteomes:UP000093180};
RA Kremer F.S., Jorge S., Oliveira N., Woloski R., Sanchez C., Navarro G.O.,
RA Brod C.S., Campos V.F., Pinto L.S., Dellagostin O.;
RT "Genome sequencing of Leptospira interrogans strain Tande.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCC28462.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MABU01000075; OCC28462.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X8WL51; -.
DR Proteomes; UP000093180; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000093180}.
FT DOMAIN 6..305
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 305 AA; 34138 MW; 782CBA9E86BD5A54 CRC64;
MKLEFSNILI YGLGLMGASL SLALKQKGIS ASITGVVGST KSKIKGQSLK SADQILTSEE
FRSTQSWKDY DFIIFGVPVD LTVKLISELP TDFSGIITDL GSTKKEIIHA VETHFSSGHN
YISSHPMCGS EESGLEFANS SLYEGRLCIL TSPKNVKLGI QDRLKNFWKF VGTTTIEISA
EEHDSILSYL SHSPHILSSI MADWAANQKT IKRYTDLSPI PLNGGGFRDM TRIAGSNPKM
WAAIFGSNQD EIFRSLSDFR DRLDIILEKL NPKNTLDPEE WERFMEISRR SRDFILKNQD
DSKKN
//
