ID A0A1X9I6F4_9CAUD Unreviewed; 451 AA.
AC A0A1X9I6F4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=TrmA family RNA methyltransferase {ECO:0000313|EMBL:ANM47707.1};
GN Name=rum {ECO:0000313|EMBL:ANM47707.1};
OS Streptococcus phage phiJH1301-2.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes.
OX NCBI_TaxID=1860194 {ECO:0000313|EMBL:ANM47707.1, ECO:0000313|Proteomes:UP000223769};
RN [1] {ECO:0000313|EMBL:ANM47707.1, ECO:0000313|Proteomes:UP000223769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774436;
RA Huang J., Ma J., Shang K., Hu X., Liang Y., Li D., Wu Z., Dai L., Chen L.,
RA Wang L.;
RT "Evolution and Diversity of the Antimicrobial Resistance Associated
RT Mobilome in Streptococcus suis: A Probable Mobile Genetic Elements
RT Reservoir for Other Streptococci.";
RL Front. Cell. Infect. Microbiol. 6:118-118(2016).
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DR EMBL; KX077896; ANM47707.1; -; Genomic_DNA.
DR Proteomes; UP000223769; Genome.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.40.50.1070; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030390; MeTrfase_TrmA_AS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002792; TRAM_dom.
DR InterPro; IPR010280; U5_MeTrfase_fam.
DR NCBIfam; TIGR00479; rumA; 1.
DR PANTHER; PTHR11061; RNA M5U METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11061:SF30; TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE; 1.
DR Pfam; PF01938; TRAM; 1.
DR Pfam; PF05958; tRNA_U5-meth_tr; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51687; SAM_MT_RNA_M5U; 1.
DR PROSITE; PS50926; TRAM; 1.
DR PROSITE; PS01230; TRMA_1; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ANM47707.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000223769};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ANM47707.1}.
FT DOMAIN 1..59
FT /note="TRAM"
FT /evidence="ECO:0000259|PROSITE:PS50926"
FT ACT_SITE 408
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10015"
SQ SEQUENCE 451 AA; 50509 MW; 80E6321CF670341B CRC64;
MLKKNDIVEV EVVDLTHEGQ GVAKIDGFVF FVDNALPGEK ISMRILKLKK NIGFGKVEQW
QSFSPDRNQD LDLTYLRTGI ADLGHLTYPA QLAFKKKQVE NSLRKIAGIS EIAVADTLGM
DNPLAYRNKA AVPVRRVNGQ LETGFFRKNS HDLVPIEDFY IQHKEIDALV LATRDLLRKL
DLKPYDEKEQ TGLVRNIVVR RGHYSGQLML VLVTTRPKIF RVETLIERLT SQFPNLVSIV
QNINDQNTNA IFGQEFRLLH GSETIVDTML GNEFEISAPS FYQVNTEMAE KLYQTAIDFA
ELSADDIVID AYSGIGTIGL SFAKQVKHVY GVEVVEKAVL DSQKNAARNG IDNATYVCDS
AESAMKKWVA DGIKPTVIFV DPPRKGLTES FIRASSSVAP EKIVYISCNA ATMARDIKLY
EELGYRLTKV RPVDLFPTTH HIECVALLVK A
//
