ID   A0A1X9LH54_9MICO        Unreviewed;       350 AA.
AC   A0A1X9LH54;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=tryptophan--tRNA ligase {ECO:0000256|ARBA:ARBA00013161};
DE            EC=6.1.1.2 {ECO:0000256|ARBA:ARBA00013161};
GN   Name=trpS {ECO:0000313|EMBL:GGI39656.1};
GN   ORFNames=B5808_00345 {ECO:0000313|EMBL:ARJ03852.1}, GCM10010988_25160
GN   {ECO:0000313|EMBL:GGI39656.1};
OS   Cnuibacter physcomitrellae.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Cnuibacter.
OX   NCBI_TaxID=1619308 {ECO:0000313|EMBL:ARJ03852.1, ECO:0000313|Proteomes:UP000192775};
RN   [1] {ECO:0000313|EMBL:ARJ03852.1, ECO:0000313|Proteomes:UP000192775}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XA {ECO:0000313|EMBL:ARJ03852.1}, and XA(T)
RC   {ECO:0000313|Proteomes:UP000192775};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:GGI39656.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CGMCC 1.15041 {ECO:0000313|EMBL:GGI39656.1};
RX   PubMed=30832757;
RA   Wu L., Ma J.;
RT   "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT   project: providing services to taxonomists for standard genome sequencing
RT   and annotation.";
RL   Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN   [3] {ECO:0000313|EMBL:GGI39656.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CGMCC 1.15041 {ECO:0000313|EMBL:GGI39656.1};
RA   Sun Q., Zhou Y.;
RL   Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363036}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP020715; ARJ03852.1; -; Genomic_DNA.
DR   EMBL; BMHD01000001; GGI39656.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X9LH54; -.
DR   STRING; 1619308.B5808_00345; -.
DR   KEGG; cphy:B5808_00345; -.
DR   Proteomes; UP000192775; Chromosome.
DR   Proteomes; UP000633908; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004830; F:tryptophan-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006436; P:tryptophanyl-tRNA aminoacylation; IEA:InterPro.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 1.10.240.10; Tyrosyl-Transfer RNA Synthetase; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002305; aa-tRNA-synth_Ic.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR002306; Trp-tRNA-ligase.
DR   NCBIfam; TIGR00233; trpS; 1.
DR   PANTHER; PTHR43766; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43766:SF1; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00579; tRNA-synt_1b; 1.
DR   PRINTS; PR01039; TRNASYNTHTRP.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363036};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363036};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363036};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192775}.
SQ   SEQUENCE   350 AA;  38161 MW;  1B30138721F8CCE0 CRC64;
     MDSFAATQAR MADLDDRIRA DPARFRVLTG ERPTGRLHLG HYFGTLAGRV LLQDRGVEVF
     LVLADYQVIT DRNTSRDVVA NVHEAVLDYL AAGLDPAATT IFPHSAVPSL NQLLLPFLSL
     VTEAELHRNP TVKAETAASG RALSGLMLTY PVHQAADILF CKGNLVPVGK DNLPHIEMTR
     TIARRFTERY GALFPEPEPL VTASPEVPGV DGMKMSKSRG NAIALGMTED ETAAVIRRAK
     TDGERRITFD PVARPGVSAL LTTASLCTMT PPEVIADEIG DRGSSELKRV TTDAVNARFA
     DHRRRRSELA ADPGVIDEVL TAGIERANAI ADRTLDEVRE RMGMRYLARA
//