ID A0A1X9LYZ5_9MICO Unreviewed; 565 AA.
AC A0A1X9LYZ5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:ARJ07280.1};
GN ORFNames=B5808_07915 {ECO:0000313|EMBL:ARJ07280.1};
OS Cnuibacter physcomitrellae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Cnuibacter.
OX NCBI_TaxID=1619308 {ECO:0000313|EMBL:ARJ07280.1, ECO:0000313|Proteomes:UP000192775};
RN [1] {ECO:0000313|EMBL:ARJ07280.1, ECO:0000313|Proteomes:UP000192775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XA(T) {ECO:0000313|Proteomes:UP000192775};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP020715; ARJ07280.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X9LYZ5; -.
DR STRING; 1619308.B5808_07915; -.
DR KEGG; cphy:B5808_07915; -.
DR Proteomes; UP000192775; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000192775};
KW Transferase {ECO:0000313|EMBL:ARJ07280.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 30..181
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 235..542
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 565 AA; 59117 MW; 42286F5286569EDD CRC64;
MVRLVSIQIV QADELNAQAF DKLSAQTETY GLRGDITDSD GTVLATTVLT YDVTVAPNQV
VDLEKTDDAG TTTTVTPRQI AESIAAITGQ SADEVYAAFT SDPTSNFAYV VKGISVDQFR
AIRDLGVDWL YYSSVPKRTY PNGAVAGSVV GFVGSDGTGQ AGVEQLDQTC LAGTDGVQTY
LRSGDNGGVA IPGSTETTVQ AQDGGTVVLT LDSDLQYFAQ QTLAARVQEV QGAWGTVVVQ
EVKTGKLLAV ADYPSVDPNN VDGTDPANRG SIAFQAPFEP GSTFKALTAA SLVDSGTANV
GTQVEAPYVY TDANGASTKD SEFHTDPLRL TLAGVIQESS NTGTAMLGEQ MSPEQRYDYM
MKFHLGEASE VGFPAESGGI IHPWDEWDDQ TNMTTTFGQG LSTTAVQVAS MYQALGNGGV
RLPVQLVEGC KQADGSMTDV PSGSGEQVVS AQAATDTVNM LETVVTGGYA SKDLQIPGYR
VAAKTGTAQM SDGNGAYGSS YITSLAGLAP ADDPQYVVSV TIAKPVTVES ALAAAPVFQK
IMSQVLKEHR VQPSTVPAPD LPTTY
//
