ID A0A1X9MDE0_9BACI Unreviewed; 699 AA.
AC A0A1X9MDE0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=High-affinity Na(+)/H(+) antiporter NhaS3 {ECO:0000313|EMBL:ARK31447.1};
GN Name=nhaS3 {ECO:0000313|EMBL:ARK31447.1};
GN ORFNames=BkAM31D_17265 {ECO:0000313|EMBL:ARK31447.1};
OS Halalkalibacter krulwichiae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halalkalibacter.
OX NCBI_TaxID=199441 {ECO:0000313|EMBL:ARK31447.1, ECO:0000313|Proteomes:UP000193006};
RN [1] {ECO:0000313|EMBL:ARK31447.1, ECO:0000313|Proteomes:UP000193006}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM31D {ECO:0000313|EMBL:ARK31447.1,
RC ECO:0000313|Proteomes:UP000193006};
RA Krulwich T.A., Anastor L., Ehrlich R., Ehrlich G.D., Janto B.;
RT "Bacillus krulwichiae AM31D Genome sequencing and assembly.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP020814; ARK31447.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X9MDE0; -.
DR STRING; 199441.BkAM31D_17265; -.
DR KEGG; bkw:BkAM31D_17265; -.
DR Proteomes; UP000193006; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR CDD; cd01988; Na_H_Antiporter_C; 1.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43562:SF4; NA(+)_H(+) ANTIPORTER NHAS5; 1.
DR PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000193006};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..379
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 699 AA; 76905 MW; 2CE6866682F84B16 CRC64;
MITQPVTNPV LIFAIAMVIF LVAPLIMAKL RIPGIIGFIF AGVIVGPNGL GILDRDPTII
LLGTVGLLYI IFIAGLEIDL EGFKKYRNRS LTFGTMSFTI PFILGTMGAY LLGYSVAGAI
LLGSLLGSHT LLAYPIASRL GISKNKAVTT SVGGTIMTDT LALLILAVVA GSTQGELTAD
FWFVLIVSLI IYVAGVFIIV PIAAKFFFRT LSSEGTLEYI FVMTVLFVSA FFATVAGLEP
IIGAFLAGLA LNRFLFEQSP LMNRIKFIGN SLFIPFFLLS VGMLMDLRIL IYEPQAWVKA
ALVVILVISG KFMAAWIAGK IYRYSIEEVK LMFGLTIPQA AATLAATLVG FDLGLFDQAT
VNAIIVMILI TCMIGPYTVE KFARMIAMLE EQKPYEPSQA PERVLVPIAN PNTMESLMDL
SFIVRGQSPQ PLFTLAVAQG GKEDSESRIV QAEKILSHSK VYAAGAEVPI QMLTRIDTNI
TSGILRAMEE SRITTAVIGW NGKLSTPQKI FGGILDQLLE RSTQMVLVSK LGHPLNTTKR
IVIIIPSGFD HKAGYYQSVK TAKLLASQLG ATITCYVVKD HLNSYARTFN EMKPDVKVTM
TSLLSWNEWH NMYMPLLRSD DIVLVFSARR GTIAWHPQLE RLPRVLAHSG PESFIMVYPP
ETEEVDLRGT REQNCQKHLC LKVLMNKVVT MNFKRRISH
//
