ID A0A1X9YAB8_9SPHN Unreviewed; 482 AA.
AC A0A1X9YAB8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=MATE efflux family protein {ECO:0000313|EMBL:ARS25772.1};
GN ORFNames=KC8_00490 {ECO:0000313|EMBL:ARS25772.1};
OS Sphingomonas sp. KC8.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1030157 {ECO:0000313|EMBL:ARS25772.1, ECO:0000313|Proteomes:UP000194475};
RN [1] {ECO:0000313|EMBL:ARS25772.1, ECO:0000313|Proteomes:UP000194475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KC8 {ECO:0000313|EMBL:ARS25772.1};
RA Chen Y.-L., Yu C.-P., Hu A., Lee T.-H., Yang F.-C., Ismail W., Wang P.-H.,
RA Wang C.-H., Goh K.-S., Shih C.-J., Chiang Y.-R.;
RT "Bacteria use an extradiol dioxygenase-mediated pathway to degrade natural
RT estrogens in aquatic ecosystems.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP016306; ARS25772.1; -; Genomic_DNA.
DR RefSeq; WP_029624500.1; NZ_CP016306.1.
DR AlphaFoldDB; A0A1X9YAB8; -.
DR STRING; 1030157.GCA_000214335_02186; -.
DR KEGG; spkc:KC8_00490; -.
DR eggNOG; COG0534; Bacteria.
DR OrthoDB; 9806302at2; -.
DR Proteomes; UP000194475; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13138; MATE_yoeA_like; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43549; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR PANTHER; PTHR43549:SF2; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000194475};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 482 AA; 51036 MW; 4ADDBAC9516C91E2 CRC64;
MTARAGQDLT SGPIVRTLLL FALPTLGSSI LQSLNGSINA IWVGQFLGEA ALAATANANL
VMFLMFSAVF GFGMAATILV GQNMGARNVD GVRRVIGTTT GMFVIAASLV AIAGWYGAPA
LLHLLATPPE VFDFALAYLR VIFLGLPPGM IVVLLTMGLR GTGDSMTPLW FMALSAVIDV
VMNPVLILGL GPAPRMGIEG AATATLIANY AGLIGLVGYI YWRDLPLRLR GRELAYLLPD
PKLLRTIVLK GVPMGMQMLV VSISALAMIG LVNREGAATT AAYGAANQMW TYIQMPAMAL
GAAVSAMAAQ NIGAGRWERV GQITRAGIGI NILMTGSAVL LLLAIDRYVL SLFLGSDGHA
MDIARHMNLI VSWGFILFGI TSVLSAAVRA NGAVMVPLLI LAISFIPVRL GLAAHFQPLI
GADAIWWSYN AGAIATLLMT WAYYRWGGWR TIHMMAPTDP VEAEEMVMSE AEPVGRAHPT
GV
//
