ID A0A1X9YGE5_9SPHN Unreviewed; 572 AA.
AC A0A1X9YGE5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=KC8_11375 {ECO:0000313|EMBL:ARS27884.1};
OS Sphingomonas sp. KC8.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1030157 {ECO:0000313|EMBL:ARS27884.1, ECO:0000313|Proteomes:UP000194475};
RN [1] {ECO:0000313|EMBL:ARS27884.1, ECO:0000313|Proteomes:UP000194475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KC8 {ECO:0000313|EMBL:ARS27884.1};
RA Chen Y.-L., Yu C.-P., Hu A., Lee T.-H., Yang F.-C., Ismail W., Wang P.-H.,
RA Wang C.-H., Goh K.-S., Shih C.-J., Chiang Y.-R.;
RT "Bacteria use an extradiol dioxygenase-mediated pathway to degrade natural
RT estrogens in aquatic ecosystems.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP016306; ARS27884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X9YGE5; -.
DR STRING; 1030157.GCA_000214335_01522; -.
DR KEGG; spkc:KC8_11375; -.
DR eggNOG; COG3706; Bacteria.
DR Proteomes; UP000194475; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000194475};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..572
FT /note="diguanylate cyclase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011008571"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 429..562
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 572 AA; 60136 MW; FD26128B91DD14AA CRC64;
MIGRGILFAI LLALGLAGSA SATTPRIIGL DRSVCHAVTP VSAHDSIPDA AAFGCTGEPT
GYQHQMLWLQ ADLAAPGADP GAQTLLIHQS RFDRLIVAFA YADGVVRRSE VRRGAFGSRW
RIGGQIAFEA PDRSAALVGL TIGFERLASH DLLRARLMPS RIADVAGSLA AAFIGGALTL
LFVGALYNLA LAHAVRRRFI AWHGAWAACM LLWGMLWSQL ALVIVPEVAG TLASQMCTAL
ATLAVACATA SAITSLEPGM LPPRIRHGVL ALGGAVALVG LYAAMALDGS VDWLGAVLGV
LILADLAAVA ACIALAWRRG SVEARDFALA WAPPMATLAL TQFFDMSNLL FGGGSQIAIL
IASALQTVWL SIAVTRRLAK LRAERDAARA AQIELDTLAR RDSLTGLLNR RGFIPIASAA
LREAEQGGPA LGLLLIDVDH FKAVNDRFGH DVGDAVLQRI ADRLRQWEGE ICTAGRLGGE
EFILCVRGLA IRPLAEFADR VRSGIAEADY SDLLGDGGGV TVSIGITDAG AAATFQGLYR
VADQALYEAK RAGRNRIALP PADRLSSAIE AA
//
