ID A0A1X9YHD0_9SPHN Unreviewed; 444 AA.
AC A0A1X9YHD0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:ARS28259.1};
GN ORFNames=KC8_13330 {ECO:0000313|EMBL:ARS28259.1};
OS Sphingomonas sp. KC8.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1030157 {ECO:0000313|EMBL:ARS28259.1, ECO:0000313|Proteomes:UP000194475};
RN [1] {ECO:0000313|EMBL:ARS28259.1, ECO:0000313|Proteomes:UP000194475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KC8 {ECO:0000313|EMBL:ARS28259.1};
RA Chen Y.-L., Yu C.-P., Hu A., Lee T.-H., Yang F.-C., Ismail W., Wang P.-H.,
RA Wang C.-H., Goh K.-S., Shih C.-J., Chiang Y.-R.;
RT "Bacteria use an extradiol dioxygenase-mediated pathway to degrade natural
RT estrogens in aquatic ecosystems.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP016306; ARS28259.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X9YHD0; -.
DR STRING; 1030157.GCA_000214335_00007; -.
DR KEGG; spkc:KC8_13330; -.
DR eggNOG; COG1309; Bacteria.
DR Proteomes; UP000194475; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR039536; TetR_C_Proteobacteria.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF14246; TetR_C_7; 2.
DR Pfam; PF00440; TetR_N; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS50977; HTH_TETR_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000194475}.
FT DOMAIN 27..87
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DOMAIN 252..312
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 50..69
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT DNA_BIND 275..294
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 230..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 49595 MW; 61737C057DC62405 CRC64;
MDINRRAGLL AKPRRRTASV PFMTAEIDRQ TRILDAAERR FLVDGFERCS VESIANDARA
SKREIYRDWK SKSDLFIAVA NRIFADADVD LLAARPENRE MRPTLVFLAR HLFDLFVTDR
NRDLFRASVV AIRHFPDLAS DIHSKRLTAW AQFGGYFEEL IAGNKIQVAG AYAAANRFGS
LCVEGSRYLL GYPAPAEPIR AMQSAKMVDL FLNGYRVSAA DPLADPIGQD QQAAHAATSP
VTRPPVQTRM SPHKQAAMFD ALLREFLEKG YHRANMAIVA TAVGASKSTI YRQFGSKEGG
FEQLVMRRVQ QLAEAEPFAL IPGETLESAL ARLCRNILDR HLTPDNIAIV RALIEESRTF
PELGRKYYDS ALMLSVRALR MVLHHYDVAE PDDPTVRAFH VLATYGSRFI AFPTPPNDDE
RAALSDEATA IFLHGVAVSQ ESSQ
//
