ID A0A1Y0FSZ0_9GAMM Unreviewed; 356 AA.
AC A0A1Y0FSZ0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=CBR65_03385 {ECO:0000313|EMBL:ARU26538.1};
OS Cellvibrio sp. PSBB006.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Cellvibrionaceae; Cellvibrio.
OX NCBI_TaxID=1987723 {ECO:0000313|EMBL:ARU26538.1, ECO:0000313|Proteomes:UP000196143};
RN [1] {ECO:0000313|EMBL:ARU26538.1, ECO:0000313|Proteomes:UP000196143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PSBB006 {ECO:0000313|EMBL:ARU26538.1,
RC ECO:0000313|Proteomes:UP000196143};
RA Song R., Chenine A.L., Ruprecht R.M.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; CP021382; ARU26538.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y0FSZ0; -.
DR KEGG; cell:CBR65_03385; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000196143; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000196143};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 80..279
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 356 AA; 39516 MW; BA3BF230E6D8B2F9 CRC64;
MLKKLAVIAA CIVILMTIAI SFFIHWVGEF TPSDSALRAL AATEVKDISY LRDRPIPTHG
KILAIVTSTR ELGDTGKITG YELSELARAY WVFSANGFEV DIASPEGDEP HAIIDDEDMN
EYDYAFLNDI TAQKKAKTTI KVSDVDPDNY SALYFVGGKG AMFDFPDNPA IKDLIHKFYT
EGKVISAICH GPAALVNVKV QDEWLVSGRA ISAFTKSEEL LLMPDARSIF PFLLQEKLEE
RGAQFFSTND YLNQVSVSGK LITAQNPWST WSIAEEVVKK IGYEPKPRKL TREERSVSLL
QEFYSGGLNA AENLIKGSPE KYNGHLVLMH AVVAAMKYDV ENAVKLIVLA ESLRPK
//
